Rab GTPases as coordinators of vesicle traffic (Q28131746)

postsynaptic early endosome

Europe PubMed Central

title

Rab GTPases as coordinators of vesicle traffic (English)

0 references

main subject

1 reference

Gene Ontology release 2020-05-02

1

Harald Stenmark

0 references

language of work or name

English

0 references

publication date

August 2009

0 references

published in

Nature Reviews Molecular Cell Biology

0 references

volume

10

0 references

page(s)

513-25

0 references

issue

8

0 references

cites work

Rab GTPases at a glance

1 reference

Evolution of the Rab family of small GTP-binding proteins

31 March 2020

1 reference

Rab proteins as membrane organizers

31 March 2020

1 reference

Structural clues to Rab GTPase functional diversity

31 March 2020

1 reference

Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5.

31 March 2020

1 reference

Structural basis of family-wide Rab GTPase recognition by rabenosyn-5

31 March 2020

1 reference

Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells

31 March 2020

1 reference

TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.

31 March 2020

1 reference

Protrudin induces neurite formation by directional membrane trafficking

31 March 2020

1 reference

Molecular cloning and characterization of a novel type of regulatory protein (GDI) for smg p25A, a ras p21-like GTP-binding protein

31 March 2020

1 reference

Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange

31 March 2020

1 reference

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange

31 March 2020

1 reference

Mechanism of digeranylgeranylation of Rab proteins. Formation of a complex between monogeranylgeranyl-Rab and Rab escort protein

31 March 2020

1 reference

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

31 March 2020

1 reference

Yip3 catalyses the dissociation of endosomal Rab–GDI complexes

31 March 2020

1 reference

Role of Rab9 GTPase in facilitating receptor recruitment by TIP47

31 March 2020

1 reference

A novel role for Rab5-GDI in ligand sequestration into clathrin-coated pits.

31 March 2020

1 reference

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

31 March 2020

1 reference

Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by rab5 and hRME-6

31 March 2020

1 reference

Phosphatidylinositol-3-OH kinases are Rab5 effectors.

31 March 2020

1 reference

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

31 March 2020

1 reference

Ypt11 functions in bud-directed transport of the Golgi by linking Myo2 to the coatomer subunit Ret2.

31 March 2020

1 reference

Rab GTPases and myosin motors in organelle motility

31 March 2020

1 reference

Identification of an organelle receptor for myosin-Va

31 March 2020

1 reference

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

31 March 2020

1 reference

Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes.

31 March 2020

1 reference

Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling

31 March 2020

1 reference

Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3.

31 March 2020

1 reference

Interaction of a Golgi-associated kinesin-like protein with Rab6

31 March 2020

1 reference

The human kinesin-like protein RB6K is under tight cell cycle control and is essential for cytokinesis.

31 March 2020

1 reference

Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B

31 March 2020

1 reference

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

31 March 2020

1 reference

Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex

31 March 2020

1 reference

A ras-like protein is required for a post-Golgi event in yeast secretion

31 March 2020

1 reference

The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis

31 March 2020

1 reference

Spatial regulation of the exocyst complex by Rho1 GTPase

31 March 2020

1 reference

rab5 controls early endosome fusion in vitro

31 March 2020

1 reference

Selective membrane recruitment of EEA1 suggests a role in directional transport of clathrin-coated vesicles to early endosomes

31 March 2020

1 reference

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

31 March 2020

1 reference

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

31 March 2020

1 reference

Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain

31 March 2020

1 reference

Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45.

31 March 2020

1 reference

The Rab5 effector EEA1 interacts directly with syntaxin-6

31 March 2020

1 reference

Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13

31 March 2020

1 reference

Versatile role of Rab27 in membrane trafficking: focus on the Rab27 effector families.

31 March 2020

1 reference

The Slp4-a linker domain controls exocytosis through interaction with Munc18-1.syntaxin-1a complex.

31 March 2020

1 reference

Granuphilin molecularly docks insulin granules to the fusion machinery.

31 March 2020

1 reference

The C2B domain of rabphilin directly interacts with SNAP-25 and regulates the docking step of dense core vesicle exocytosis in PC12 cells

31 March 2020

1 reference

The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance.

31 March 2020

1 reference

Defining the functions of trans-SNARE pairs

31 March 2020

1 reference

Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion

31 March 2020

1 reference

Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis--Golgi tethering

31 March 2020

1 reference

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

31 March 2020

1 reference

A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function

31 March 2020

1 reference

TRAPP stimulates guanine nucleotide exchange on Ypt1p

31 March 2020

1 reference

The TRAPP complex is a nucleotide exchanger for Ypt1 and Ypt31/32.

31 March 2020

1 reference

The Structural Basis for Activation of the Rab Ypt1p by the TRAPP Membrane-Tethering Complexes

31 March 2020

1 reference

New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion

31 March 2020

1 reference

Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11

31 March 2020

1 reference

Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells

31 March 2020

1 reference

TIP47 is a key effector for Rab9 localization

31 March 2020

1 reference

Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes.

31 March 2020

1 reference

Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.

31 March 2020

1 reference

Multiple Rab GTPase binding sites in GCC185 suggest a model for vesicle tethering at the trans-Golgi.

31 March 2020

1 reference

A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling

31 March 2020

1 reference

Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins

31 March 2020

1 reference

Large scale screening for novel rab effectors reveals unexpected broad Rab binding specificity.

31 March 2020

1 reference

The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms

31 March 2020

1 reference

Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides

31 March 2020

1 reference

Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.

31 March 2020

1 reference

Rab conversion as a mechanism of progression from early to late endosomes

31 March 2020

1 reference

Signaling on the endocytic pathway

31 March 2020

1 reference

Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway

31 March 2020

1 reference

Rab7 activation by growth factor withdrawal contributes to the induction of apoptosis

31 March 2020

1 reference

Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a

31 March 2020

1 reference

Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1.

31 March 2020

1 reference

Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases

31 March 2020

1 reference

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

31 March 2020

1 reference

Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration

31 March 2020

1 reference

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment

31 March 2020

1 reference

The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development

31 March 2020

1 reference

Regulation of endocytosis via the oxygen-sensing pathway

31 March 2020

1 reference

31 March 2020

Virus entry: open sesame

1 reference

Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5

31 March 2020

1 reference

A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium

31 March 2020

1 reference

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

31 March 2020

1 reference

Phagosome maturation: going through the acid test

31 March 2020

1 reference

Imaging of Rab5 activity identifies essential regulators for phagosome maturation

31 March 2020

1 reference

Helicobacter pylori VacA toxin promotes bacterial intracellular survival in gastric epithelial cells

31 March 2020

1 reference

Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7.

31 March 2020

1 reference

Inhibition of Rab5a exchange activity is a key step for Listeria monocytogenes survival.

31 March 2020

1 reference

SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34

31 March 2020

1 reference

Legionella pneumophila proteins that regulate Rab1 membrane cycling

31 March 2020

1 reference

A bifunctional bacterial protein links GDI displacement to Rab1 activation

31 March 2020

1 reference

31 March 2020

Endocytosis and cancer.

1 reference

Defective downregulation of receptor tyrosine kinases in cancer

31 March 2020

1 reference

The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

31 March 2020

1 reference

Regulation of vesicle trafficking in madin-darby canine kidney cells by Rab11a and Rab25

31 March 2020

1 reference

Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments

31 March 2020

1 reference

Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins

31 March 2020

1 reference

Integrin trafficking regulated by Rab21 is necessary for cytokinesis

31 March 2020

1 reference

MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway.

31 March 2020

1 reference

Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer

31 March 2020

1 reference

Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells

31 March 2020

1 reference

Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse

31 March 2020

1 reference

Retinal degeneration in choroideremia: deficiency of rab geranylgeranyl transferase

31 March 2020

1 reference

Deficient geranylgeranylation of Ram/Rab27 in choroideremia.

31 March 2020

1 reference

Mutations of the catalytic subunit of RAB3GAP cause Warburg Micro syndrome

31 March 2020

1 reference

Mutation in Rab3 GTPase-activating protein (RAB3GAP) noncatalytic subunit in a kindred with Martsolf syndrome

31 March 2020

1 reference

Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy

31 March 2020

1 reference

AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain

31 March 2020

1 reference

Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1

31 March 2020

1 reference

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

31 March 2020

1 reference

Rab10 in insulin-stimulated GLUT4 translocation.

31 March 2020

1 reference

RAB23 mutations in Carpenter syndrome imply an unexpected role for hedgehog signaling in cranial-suture development and obesity

31 March 2020

1 reference

Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse

31 March 2020

1 reference

The role of Rab3A in neurotransmitter release.

31 March 2020

1 reference

The Rab8 GTPase regulates apical protein localization in intestinal cells.

31 March 2020

1 reference

Mutation of melanosome protein RAB38 in chocolate mice

31 March 2020

1 reference

Rab5 regulates motility of early endosomes on microtubules

31 March 2020

1 reference

The Rab5 effector EEA1 is a core component of endosome docking

31 March 2020

1 reference

The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro

31 March 2020

1 reference

Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells

31 March 2020

1 reference

Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2

31 March 2020

1 reference

Identification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteins

31 March 2020

1 reference

Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation

31 March 2020

1 reference

Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis

31 March 2020

1 reference

The Rab5 guanine nucleotide exchange factor Rabex-5 binds ubiquitin (Ub) and functions as a Ub ligase through an atypical Ub-interacting motif and a zinc finger domain

31 March 2020

1 reference

Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes

31 March 2020

1 reference

Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation

31 March 2020

1 reference

Phosphorylation of GDI and membrane cycling of rab proteins

31 March 2020

1 reference

Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5

31 March 2020

1 reference

The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis

31 March 2020

1 reference

Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and Rab11

31 March 2020

1 reference

Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis

31 March 2020

1 reference

Functional dissection of Rab GTPases involved in primary cilium formation

31 March 2020

1 reference

Reversible phosphorylation--dephosphorylation determines the localization of rab4 during the cell cycle

31 March 2020

1 reference

12 December 2020

Nucleotide dependence of Rab geranylgeranylation. Rab escort protein interacts preferentially with GDP-bound Rab.

1 reference

12 December 2020

Membrane identity and GTPase cascades regulated by toggle and cut-out switches

1 reference

12 December 2020

Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins

1 reference

12 December 2020

The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer

1 reference

12 December 2020

Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM2728

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

199694

1011177487

0 references

Fatcat ID

release_732kwr5435g2bhwvmbsii4zfsy

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/732kwr5435g2bhwvmbsii4zfsy

24 November 2022

mapped directly with Wikidata item

199694

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference