Met receptor tyrosine kinase: enhanced signaling through adapter proteins (Q28140219)

A member of the Met/HGF-receptor family is expressed in a BMP-4-like pattern in the ectoderm of Xenopus gastrulae.

Europe PubMed Central

title

Met receptor tyrosine kinase: enhanced signaling through adapter proteins (English)

0 references

author name string

K A Furge

series ordinal

1

0 references

Y W Zhang

series ordinal

2

0 references

G F Vande Woude

series ordinal

3

0 references

language of work or name

English

0 references

publication date

20 November 2000

0 references

published in

Oncogene

0 references

volume

19

0 references

page(s)

5582-9

0 references

issue

49

0 references

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Molecular cloning of the Xenopus c-met/hepatocyte growth factor receptor and its regional expression during early development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

A Peptide Representing the Carboxyl-terminal Tail of the Met Receptor Inhibits Kinase Activity and Invasive Growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Stat3 activation is required for cellular transformation by v-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Three receptor genes for plasminogen related growth factors in the genome of the puffer fish Fugu rubripes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Characterization of the rearranged tpr-met oncogene breakpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Physiological signals and oncogenesis mediated through Crk family adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Effect of potent and selective inhibitors of the Grb2 SH2 domain on cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Tyrosine kinase receptor indistinguishable from the c-met protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Scatter factor induces blood vessel formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Activating mutations for the met tyrosine kinase receptor in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 tran

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

A novel viral oncogene with structural similarity to phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Purification and subunit structure of hepatocyte growth factor from rat platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and inducti

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Mechanism of met oncogene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Activation of the JNK pathway is essential for transformation by the Met oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Purified scatter factor stimulates epithelial and vascular endothelial cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Constitutive activation of the RON gene promotes invasive growth but not transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

How receptor tyrosine kinases activate Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Scatter factor/hepatocyte growth factor is essential for liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

A novel protease obtained from FBS-containing culture supernatant, that processes single chain form hepatocyte growth factor to two chain form in serum-free culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Expression of HGF/SF, HGF1/MSP, and c-met suggests new functions during early chick development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The met proto-oncogene receptor and lumen formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The Met proto-oncogene mesenchymal to epithelial cell conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Chicken macrophage stimulating protein is a ligand of the receptor protein-tyrosine kinase Sea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Chromosomal localization of rat hepatocyte growth factor (Hgf) and HGF receptor (Met) and characterization of HGF receptor cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

Affinity and specificity requirements for the first Src homology 3 domain of the Crk proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

Differential requirement of Grb2 and PI3-kinase in HGF/SF-induced cell motility and tubulogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

Involvement of hepatocyte growth factor in kidney development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

Evaluation of the tyrosine kinase domain of the Met proto-oncogene in sporadic ovarian carcinomas*

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203859

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203859

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

5102272

1017661502

0 references

5102272

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference