Immunological concepts of vaccine adjuvant activity (Q28141017)

Current Opinion in Immunology

Europe PubMed Central

title

Immunological concepts of vaccine adjuvant activity (English)

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V E Schijns

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language of work or name

English

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publication date

August 2000

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published in

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volume

12

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issue

4

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page(s)

456-63

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cites work

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Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

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Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction

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Antibody and cytokine responses in efferent lymph following vaccination with different adjuvants

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Inflammatory response and antigen localization following immunization with influenza virus ISCOMs

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Cytokines as potential vaccine adjuvants

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DNA vaccination with cytokine fusion constructs biases the immune response to ovalbumin.

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Defective inflammatory response in interleukin 6-deficient mice

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Neither interleukin-6 nor signalling via tumour necrosis factor receptor-1 contribute to the adjuvant activity of Alum and Freund's adjuvant

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In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production

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Preservation of mucosal and systemic adjuvant properties of ISCOMS in the absence of functional interleukin-4 or interferon-gamma.

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

10899018

1 reference

Consolidated OpenCitations Corpus – April 2017