The translation initiation factor, hu-Sui1 may be a target of hepatitis B X antigen in hepatocarcinogenesis (Q28141874)

2

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J Liu

3

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S Zhang

4

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M Zhu

5

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P Arbuthnot

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M Kew

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M A Feitelson

Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

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language of work or name

English

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publication date

4 March 1999

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published in

Oncogene

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volume

18

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issue

9

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page(s)

1677-87

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cites work

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The hepatitis B virus X gene induces p53-mediated programmed cell death

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The Mof2/Sui1 protein is a general monitor of translational accuracy

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Presence of antibodies to the polymerase gene product(s) of hepatitis B and woodchuck hepatitis virus in natural and experimental infections

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Monoclonal antibodies raised to purified woodchuck hepatitis virus core antigen particles demonstrate X antigen reactivity

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Expressed sequence tags identify a human isolog of the suil translation initiation factor

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Inhibition of cyclin-dependent kinases by p21

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Hepatitis B virus transcriptional activators: mechanisms and possible role in oncogenesis

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Characteristics of hepatitis B X antigen, antibodies to X antigen, and antibodies to the viral polymerase during hepatitis B virus infection

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Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

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HBx gene of hepatitis B virus induces liver cancer in transgenic mice

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X-gene product of hepatitis B virus induces apoptosis in liver cells

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Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen

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Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts

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HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions

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Three sites of the hepatitis B virus X protein cooperatively interact with cellular proteins

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Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

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Hepatitis B virus X protein interferes with cellular DNA repair.

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Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation

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Products of the "X" gene in hepatitis B and related viruses

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Hepatitis B virus X protein interacts with a probable cellular DNA repair protein

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Two-codon insertion mutations of the HBx define two separate regions necessary for its trans-activation function

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Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host

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Transcriptional trans-activating function of hepatitis B virus.

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HBxAg in the liver from carrier patients with chronic hepatitis and cirrhosis

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The value of hepatitis B x antigen as a prognostic marker in the development of hepatocellular carcinoma

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