NAK is an IkappaB kinase-activating kinase (Q28143033)

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A Fujimoto

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Y Chen

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S Hatakeyama

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K Nakayama

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Y Kaneko

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Y Nimura

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N Motoyama

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K Ikeda

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M Karin

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M Nakanishi

The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation

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language of work or name

English

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publication date

13 April 2000

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published in

Nature

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volume

404

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page(s)

778-82

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issue

6779

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cites work

1 reference

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

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Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

1 reference

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

1 reference

IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

1 reference

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

1 reference

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

1 reference

JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?

21 January 2018

1 reference

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

21 January 2018

1 reference

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

21 January 2018

1 reference

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

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Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

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Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

21 January 2018

1 reference

NF-kappa B: ten years after

21 January 2018

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Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

21 January 2018

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The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

21 January 2018

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

21 January 2018

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A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death

21 January 2018

1 reference

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

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NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

21 January 2018

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Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase

21 January 2018

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A mouse embryonic stem cell line showing pluripotency of differentiation in early embryos and ubiquitous beta-galactosidase expression

21 January 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

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Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes

21 January 2018

1 reference

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Evidence that protein kinase Cepsilon mediates phorbol ester inhibition of calphostin C- and tumor necrosis factor-alpha-induced apoptosis in U937 histiocytic lymphoma cells

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