Maturation of HIV envelope glycoprotein precursors by cellular endoproteases (Q28143090)

Biochimica et Biophysica Acta

Europe PubMed Central

title

Maturation of HIV envelope glycoprotein precursors by cellular endoproteases (English)

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author name string

M Moulard

series ordinal

1

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E Decroly

series ordinal

2

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language of work or name

English

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publication date

10 November 2000

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published in

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volume

1469

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issue

3

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page(s)

121-32

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cites work

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Comparative functional role of PC7 and furin in the processing of the HIV envelope glycoprotein gp160

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Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines

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Expression and characterization of a functional human immunodeficiency virus envelope glycoprotein in insect cells

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7 January 2021

The proprotein convertases

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7 January 2021

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PC8 [corrected], a new member of the convertase family

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cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases

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Mammalian subtilisins: the long-sought dibasic processing endoproteases

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[11] Biochemical and genetic methods for analyzing specificity and activity of a precursor-processing enzyme: Yeast Kex2 protease, kexin

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T4-lymphocyte endoprotease responsible for the proteolytic processing of HIV-1 gp160, like Kex2p endoprotease, is a calcium-dependent enzyme.

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7 January 2021

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

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Processing and routage of HIV glycoproteins by furin to the cell surface

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7 January 2021

Legitimate and illegitimate cleavage of human immunodeficiency virus glycoproteins by furin

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Comparative processing of bovine leukemia virus envelope glycoprotein gp72 by subtilisin/kexin-like mammalian convertases.

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Defective posttranslational processing activates the tyrosine kinase encoded by the MET proto-oncogene (hepatocyte growth factor receptor).

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7 January 2021

Occurrence of an HIV-1 gp160 endoproteolytic activity in low-density vesicles and evidence for a distinct density distribution from endogenously expressed furin and PC7/LPC convertases

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A novel mechanism for the acquisition of virulence by a human influenza A virus

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The synthesis of inhibitors for processing proteinases and their action on the Kex2 proteinase of yeast

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Proteolytic cleavage of the fusion protein but not membrane fusion is required for measles virus-induced immunosuppression in vitro

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7 January 2021

Processing of the Ebola virus glycoprotein by the proprotein convertase furin

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7 January 2021

Processing of the Borna disease virus glycoprotein gp94 by the subtilisin-like endoprotease furin

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7 January 2021

Anti-HIV activity of multibranched peptide constructs derived either from the cleavage sequence or from the transmembrane domain (gp41) of the human immunodeficiency virus type 1 envelope.

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7 January 2021

An anti-HIV peptide construct derived from the cleavage region of the Env precursor acts on Env fusogenicity through the presence of a functional cleavage sequence.

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7 January 2021

An anti-human immunodeficiency virus multiple antigen peptide encompassing the cleavage region of the env precursor interferes with membrane fusion at a post-CD4 binding step

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7 January 2021

Megalomicin inhibits HIV-1 replication and interferes with gp160 processing

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7 January 2021

A protein-based therapeutic for human cytomegalovirus infection

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7 January 2021

The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity

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7 January 2021

Understanding influenza virus pathogenicity

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