IL-15/IL-15Ralpha intracellular trafficking in human melanoma cells and signal transduction through the IL-15Ralpha (Q28143117)

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J Giron-Michel

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A Gaggero

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E Cazes

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R Meazza

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M Monetti

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E Monaco

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Z Mishal

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C Jasmin

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F Indiveri

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S Ferrini

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B Azzarone

Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes

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language of work or name

English

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publication date

26 October 2000

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published in

Oncogene

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volume

19

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issue

45

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page(s)

5153-62

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cites work

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region /IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translatio

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IL-15 is produced by a subset of human melanomas, and is involved in the regulation of markers of melanoma progression through juxtacrine loops.

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Natural splicing of exon 2 of human interleukin-15 receptor alpha-chain mRNA results in a shortened form with a distinct pattern of expression

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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Expression of two interleukin-15 mRNA isoforms in human tumors does not correlate with secretion: role of different signal peptides

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Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo

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A role for IL-15 in rheumatoid arthritis?

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Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides

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The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

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The NF-kappaB binding site is essential for transcriptional activation of the IL-15 gene

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Death deflected: IL-15 inhibits TNF-alpha-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Ralpha chain

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inferred from DOI database lookup

7 January 2021

based on heuristic

Differential intracellular trafficking, secretion and endosomal localization of two IL-15 isoforms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203873