Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation (Q28143462)

C-abl oncogene 1, non-receptor tyrosine kinase

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

F Cong

1

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S Spencer

2

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J F Côté

3

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Y Wu

4

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M L Tremblay

5

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L A Lasky

6

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S P Goff

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

7

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language of work or name

English

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publication date

December 2000

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published in

Molecular Cell

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volume

6

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issue

6

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page(s)

1413-23

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cites work

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7 January 2021

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

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Identification of a binding site in c-Ab1 tyrosine kinase for the C-terminal repeated domain of RNA polymerase II.

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation

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Characterization of a novel member of the DOK family that binds and modulates Abl signaling

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Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP-PEST as a model

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Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST

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Use of eukaryotic expression technology in the functional analysis of cloned genes

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Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

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Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein

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The S. pombe cdc15 gene is a key element in the reorganization of F-actin at mitosis.

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Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

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Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST

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Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

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Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

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7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

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Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

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Essential roles for the Abl and Arg tyrosine kinases in neurulation

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Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo

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7 January 2021

Integrins regulate the association and phosphorylation of paxillin by c-Abl

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Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport

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A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion

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Protein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptor

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Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences

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Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

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Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor

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c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

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Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites

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BCR/ABL induces multiple abnormalities of cytoskeletal function

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The nuclear tyrosine kinase c-Abl negatively regulates cell growth

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7 January 2021

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

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7 January 2021

The noncatalytic domain of protein-tyrosine phosphatase-PEST targets paxillin for dephosphorylation in vivo

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7 January 2021

Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity

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7 January 2021

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

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7 January 2021

PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase

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7 January 2021

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

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7 January 2021

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

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7 January 2021

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity

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7 January 2021

Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation

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7 January 2021

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

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7 January 2021

The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity

1 reference

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7 January 2021

PSTPIP 2, a second tyrosine phosphorylated, cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase

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7 January 2021

Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein

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Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

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7 January 2021

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

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7 January 2021

Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

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7 January 2021

c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein

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7 January 2021