Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide (Q28143503)

2

0 references

D L Johnson

3

0 references

R L Thurmond

4

0 references

Y You

5

0 references

F J McMahon

6

0 references

R Jin

7

0 references

O Livnah

8

0 references

J Tullai

9

0 references

F X Farrell

10

0 references

M A Goldsmith

11

0 references

I A Wilson

12

0 references

L K Jolliffe

Journal of Biological Chemistry

13

0 references

language of work or name

English

0 references

publication date

14 May 1999

0 references

published in

0 references

volume

274

0 references

issue

20

0 references

page(s)

14163-9

0 references

cites work

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

STATs and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: one high-affinity and one low-affinity interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Haemopoietic receptors and helical cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Refolding, purification, and characterization of human erythropoietin binding protein produced in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Small peptides as potent mimetics of the protein hormone erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Efficiency of signalling through cytokine receptors depends critically on receptor orientation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

The X-ray structure of a growth hormone-prolactin receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Solution structure of an extracellular domain containing the WSxWS motif of the granulocyte colony-stimulating factor receptor and its interaction with ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Crystal structure of a cytokine-binding region of gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

The crystal structure of the extracellular domain of human tissue factor refined to 1.7 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Crystal structure of the extracellular region of human tissue factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Identification of a critical ligand binding determinant of the human erythropoietin receptor. Evidence for common ligand binding motifs in the cytokine receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Protein engineering and the study of structure--function relationships in receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all thr

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Crucial role of the residue R280 at the F'-G' loop of the human granulocyte/macrophage colony-stimulating factor receptor alpha chain for ligand recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

The receptor binding site of human interleukin-3 defined by mutagenesis and molecular modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Crystal structure of human interleukin-10 at 1.6 A resolution and a model of a complex with its soluble receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Mutagenesis studies of the human erythropoietin receptor. Establishment of structure-function relationships.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

A hot spot of binding energy in a hormone-receptor interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Structural and functional epitopes in the growth hormone receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Hematopoietic receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Structural design and molecular evolution of a cytokine receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Quantitation of specific binding of erythropoietin to human erythroid colony-forming cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

18 Systematic mutational analyses of protein-protein interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Identification of a ligand-binding site on the granulocyte colony-stimulating factor receptor by molecular modeling and mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163

Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.20.14163