The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals (Q28144464)

2

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N Katz

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H Tillmanns

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W Haberbosch

Theodore Cooper Memorial Lecture. Hypertension and the pathogenesis of atherosclerosis. Oxidative stress and the mediation of arterial inflammatory response: a new perspective

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language of work or name

English

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publication date

August 1999

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published in

Atherosclerosis

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volume

145

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issue

2

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page(s)

315-23

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cites work

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Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells

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p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells

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Polymorphism of the NADH/NADPH oxidase p22 phox gene in patients with coronary artery disease

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Angiotensin II type 1 receptor A1166C gene polymorphism. Absence of an association with the risk of coronary artery disease and myocardial infarction and of a synergistic effect with angiotensin-converting enzyme gene polymorphism on the risk of the

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A more meaningful scoring system for determining the severity of coronary heart disease

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An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels

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A polymorphism of the angiotensinogen gene associated with variation in blood pressure in a genetic isolate

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Rapid detection of the hypertension-associated Met235-->Thr allele of the human angiotensinogen gene

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A simple molecular assay for the C1166 variant of the angiotensin II type 1 receptor gene

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Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes

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Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes

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Gene Polymorphism but not Catalytic Activity of Angiotensin I–Converting Enzyme Is Associated With Coronary Artery Disease and Myocardial Infarction in Low-Risk Patients

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ACE I/D gene polymorphism: presence of the ACE D allele increases the risk of coronary artery disease in younger individuals

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The TT genotype of the methylenetetrahydrofolate reductase C677T gene polymorphism is associated with the extent of coronary atherosclerosis in patients at high risk for coronary artery disease

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A new promoter polymorphism in the gene of lipopolysaccharide receptor CD14 is associated with expired myocardial infarction in patients with low atherosclerotic risk profile

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Are we mortgaging the medical profession?

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