Structure and expression pattern of a human MTG8/ETO family gene, MTGR1 (Q28144775)

1

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S Mitani

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N Mitsuhashi

3

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I Kitabayashi

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E Takahashi

5

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M Suzuki

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N Munakata

7

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M Ohki

Deletions of chromosome 20q and the pathogenesis of myeloproliferative disorders

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language of work or name

English

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publication date

11 January 2000

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published in

Gene

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volume

241

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issue

2

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page(s)

287-95

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cites work

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A Detailed Physical and Transcriptional Map of the Region of Chromosome 20 That Is Deleted in Myeloproliferative Disorders and Refinement of the Common Deleted Region

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

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Isolation of the Drosophila segmentation gene runt and analysis of its expression during embryogenesis.

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The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

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The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein

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ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

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Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

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t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

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Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells

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A 1.6-Mb P1-based physical map of the Down syndrome region on chromosome 21.

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Identification of mRNAs associated with programmed cell death in immature thymocytes

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ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

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Structure and expression of the human MTG8/ETO gene

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