Cyclooxygenase in the treatment of glioma: its complex role in signal transduction (Q28168685)

Cyclooxygenase-2--10 years later

Europe PubMed Central

title

Cyclooxygenase in the treatment of glioma: its complex role in signal transduction (English)

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author name string

Pamela New

series ordinal

1

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language of work or name

English

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publication date

2004

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11

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issue

3

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page(s)

152-64

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cites work

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclo-oxygenase inhibitors and thromboxane synthase inhibitors differentially regulate migration arrest, growth inhibition and apoptosis in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase-2 selective inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

The effect of selective inhibition of cyclooxygenase (COX)-2 on acute cardiac allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Efficacy of cyclooxygenase-2-specific inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenases-1 and -2 are differentially localized to microglia and endothelium in rat EAE and glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Inhibition of human brain tumor cell growth by the anti-inflammatory drug, flurbiprofen

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase inhibition in cancer--a blind alley or a new therapeutic reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Aspirin and nonsteroidal anti-inflammatory agents and risk for colorectal adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Aspirin use and chronic diseases: a cohort study of the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Inhibition of NF-kappa B by sodium salicylate and aspirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Sulindac inhibits activation of the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Role of COX-2 in carcinogenesis of colorectal cancer and its relationship with tumor biological characteristics and patients' prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Effect of p53 status on tumor response to antiangiogenic therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Ceramide Is Involved inR(+)-Methanandamide-Induced Cyclooxygenase-2 Expression in Human Neuroglioma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Ceramide regulates the transcription of cyclooxygenase-2. Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE(2) synthesis and cytotoxicity in human colorectal carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

The selective cyclooxygenase-2 inhibitor nimesulide induces apoptosis in pancreatic cancer cells independent of COX-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Prognostic significance of expression of cyclooxygenase-2 and vascular endothelial growth factor in human gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Epidermal COX-2 induction following ultraviolet irradiation: suggested mechanism for the role of COX-2 inhibition in photoprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Expression of cyclooxygenase-1 and cyclooxygenase-2 in the human prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

The role of cyclooxygenase-2 in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase-2 promotes prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Expression of cyclooxygenase-2 in human transitional cell carcinoma of the urinary bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase-2 expression in bladder cancer: correlation with poor outcome after chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase-2 as a potential target in the prevention and treatment of genitourinary tumors: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Selective cyclooxygenase-2 inhibitors and non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Expression of cyclooxygenase 2 is an independent prognostic factor in human ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Inhibition of mammary carcinogenesis by flurbiprofen, a non-steroidal antiinflammatory agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase-2 (COX-2) expression by immunohistochemistry in glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase (COX)-1 expressing macrophages/microglial cells and COX-2 expressing astrocytes accumulate during oligodendroglioma progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Signaling mechanisms involved in the activation of arachidonic acid metabolism in human astrocytoma cells by tumor necrosis factor-alpha: phosphorylation of cytosolic phospholipase A2 and transactivation of cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Effect of 4-trifluoromethyl derivatives of salicylate on nuclear factor kappaB-dependent transcription in human astrocytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Loss of Ikappa B-beta is associated with prolonged NF-kappa B activity in human glial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Effects of prostaglandin and leukotriene inhibitors on the growth of human glioma spheroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Effect of ibuprofen on tumor growth in the C6 spheroid implantation glioma model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Paradoxical effect of aspirin on the growth of C6 rat glioma and on time of development of ENU-induced tumors of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cooperative effects of matrix metalloproteinase and cyclooxygenase-2 inhibition on intestinal adenoma reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Inhibition of paclitaxel-induced apoptosis by the specific COX-2 inhibitor, NS398, in epithelial ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Increased toxicity and lack of efficacy of Rofecoxib in combination with chemotherapy for treatment of metastatic colorectal cancer: A phase II study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Selective potentiation of drug cytotoxicity by NSAID in human glioma cells: the role of COX-1 and MRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Enhancing Radiotherapy With Cyclooxygenase-2 Enzyme Inhibitors: A Rational Advance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Cyclooxygenase-2 (COX-2) enzyme inhibitors and radiotherapy: preclinical basis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Potentiation of tumor response to radiation or chemoradiation by selective cyclooxygenase-2 enzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

In vitro enhancement of tumor cell radiosensitivity by a selective inhibitor of cyclooxygenase-2 enzyme: mechanistic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Targeting angiogenic processes by combination rofecoxib and ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

COX-2 inhibitors as radiosensitizing agents for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303

Synergy between celecoxib and radiotherapy results from inhibition of cyclooxygenase-2-derived prostaglandin E2, a survival factor for tumor and associated vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107327480401100303