The perplexing role of copper-zinc superoxide dismutase in amyotrophic lateral sclerosis (Lou Gehrig's disease) (Q28184546)

amyotrophic lateral sclerosis

Europe PubMed Central

title

The perplexing role of copper-zinc superoxide dismutase in amyotrophic lateral sclerosis (Lou Gehrig's disease) (English)

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main subject

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copper

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author name string

Soshanna Zittin Potter

series ordinal

1

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Joan Selverstone Valentine

series ordinal

2

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language of work or name

English

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publication date

April 2003

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published in

Journal of Biological Inorganic Chemistry

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volume

8

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issue

4

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page(s)

373-80

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cites work

Sporadic amyotrophic lateral sclerosis with dementia and Cu/Zn superoxide dismutase-positive Lewy body-like inclusions

1 reference

12 December 2020

Increase of Cu,Zn-superoxide dismutase activity during differentiation of human K562 cells involves activation by copper of a constantly expressed copper-deficient protein

1 reference

12 December 2020

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

12 December 2020

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

12 December 2020

Current status of SOD1 mutations in familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis.

1 reference

12 December 2020

Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

1 reference

12 December 2020

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

1 reference

12 December 2020

Activation and induction by copper of Cu/Zn superoxide dismutase in Saccharomyces cerevisiae. Presence of an inactive proenzyme in anaerobic yeast

1 reference

12 December 2020

Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathological changes that most closely resemble those in human amyotrophic lateral sclerosis

1 reference

12 December 2020

Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

12 December 2020

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

1 reference

12 December 2020

Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Molecular approaches to amyotrophic lateral sclerosis

1 reference

12 December 2020

Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Reactions of hydrogen peroxide with familial amyotrophic lateral sclerosis mutant human copper-zinc superoxide dismutases studied by pulse radiolysis

1 reference

12 December 2020

In vivo peroxidative activity of FALS-mutant human CuZnSODs expressed in yeast

1 reference

12 December 2020

A pulse radiolysis study of superoxide dismutase

1 reference

12 December 2020

Superoxide anion radical (O2-.), superoxide dismutases, and related matters

1 reference

12 December 2020

Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase

1 reference

12 December 2020

Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis

1 reference

12 December 2020

A direct demonstration of the catalytic action of superoxide dismutase through the use of pulse radiolysis.

1 reference

12 December 2020

Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis

1 reference

12 December 2020

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

12 December 2020

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

1 reference

12 December 2020

Transgenic animal models of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

12 December 2020

Extensive investigations on oxidized amino acid residues in H(2)O(2)-treated Cu,Zn-SOd protein with LC-ESI-Q-TOF-MS, MS/MS for the determination of the copper-binding site

1 reference

12 December 2020