Cell-cell fusion and internalization of the CNS-based, HIV-1 co-receptor, APJ (Q28187665)

1

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Xuejun Fan

2

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Muhammad Mukhtar

3

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Jianhua Fang

4

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Charvi A Patel

5

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Garrett C DuBois

HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: independence from G protein signaling and importance of coreceptor downmodulation.

6

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language of work or name

English

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publication date

1 March 2003

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published in

Virology

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volume

307

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issue

1

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page(s)

22-36

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cites work

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HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication

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HIV blocked by chemokine antagonist

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Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate

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The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

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Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.

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The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

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Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

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Identification of a major co-receptor for primary isolates of HIV-1

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Antigen recognition by helper T cells elicits a sequence of distinct changes of their shape and intracellular calcium

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A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

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HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

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Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells.

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7 January 2021

Direct observation of endocytosis of gastrin releasing peptide and its receptor

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Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

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Dissociation of the signalling and antiviral properties of SDF-1-derived small peptides

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Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin

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Molecular properties of apelin: tissue distribution and receptor binding

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Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 that regulate signaling and receptor internalization

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The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification

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Distinct residues in the carboxyl tail mediate agonist-induced desensitization and internalization of the human dopamine D1 receptor

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Characterization of apelin, the ligand for the APJ receptor

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Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins.

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Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity

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Differential phosphorylation paradigms dictate desensitization and internalization of the N-formyl peptide receptor

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Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

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Low stringency hybridization study of the dopamine D4 receptor revealed D4-like mRNA distribution of the orphan seven-transmembrane receptor, APJ, in human brain.

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A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

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Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization

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Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting

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Bradykinin-induced internalization of the human B2 receptor requires phosphorylation of three serine and two threonine residues at its carboxyl tail.

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Ligand-induced internalization of cholecystokinin receptors. Demonstration of the importance of the carboxyl terminus for ligand-induced internalization of the rat cholecystokinin type B receptor but not the type A receptor.

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Role of the C terminus of the interleukin 8 receptor in signal transduction and internalization

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Expression and coreceptor function of APJ for primate immunodeficiency viruses

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Phosphorylation of four amino acid residues in the carboxyl terminus of the rat somatostatin receptor subtype 3 is crucial for its desensitization and internalization

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Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

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Endocytosis and recycling of the HIV coreceptor CCR5

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Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

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7 January 2021

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

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CC chemokine receptor-3 undergoes prolonged ligand-induced internalization

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7 January 2021

Apelin peptides block the entry of human immunodeficiency virus (HIV).

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7 January 2021

Identification of CXCR4 domains that support coreceptor and chemokine receptor functions

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An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus

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7 January 2021

Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation.

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7 January 2021

Patterns of chemokine receptor fusion cofactor utilization by human immunodeficiency virus type 1 variants from the lungs and blood.

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Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

4277753

4277753

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference