Structural and functional organization of the animal fatty acid synthase (Q28190255)

title

Structural and functional organization of the animal fatty acid synthase (English)

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PubMed ID

12689621

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689621

23 December 2023

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https://api.crossref.org/works/10.1016/S0163-7827(02)00067-X

23 December 2023

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23 December 2023

2

Andrzej Witkowski

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PubMed ID

12689621

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689621

23 December 2023

author name string

Stuart Smith

1

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Anil K. Joshi

3

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PubMed ID

12689621

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689621

full work available at URL

23 December 2023

language of work or name

English

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publication date

July 2003

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https://api.elsevier.com/content/article/PII:S016378270200067X?httpAccept=text/xml

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https://api.elsevier.com/content/article/PII:S016378270200067X?httpAccept=text/plain

23 December 2023

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Progress in Lipid Research

23 December 2023

published in

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volume

42

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page(s)

289-317

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issue

4

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cites work

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Mapping of functional interactions between domains of the animal fatty acid synthase by mutant complementation in vitro

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Characterization of the interthiol acyltransferase reaction catalyzed by the beta-ketoacyl synthase domain of the animal fatty acid synthase

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Distribution of reaction intermediates on chicken liver fatty acid synthase

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Mechanism of the beta-ketoacyl synthase reaction catalyzed by the animal fatty acid synthase

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The crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Synechocystis sp. at 1.54 A resolution and its relationship to other condensing enzymes

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Conversion of a beta-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine

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Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro

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Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

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Transacylation as a chain-termination mechanism in fatty acid synthesis by mammalian fatty acid synthetase. Synthesis of butyrate and hexanoate by lactating cow mammary gland fatty acid synthetase

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Specific release of the thioesterase component of the fatty acid synthetase multienzyme complex by limited trypsinization

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The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I

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Correlation of enzymatic activities and aggregation state in chicken liver fatty acid synthase

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Characterization of fatty acid synthase monomers restrained from reassociating by immobilization to a solid support

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Release of two thioesterase domains from fatty acid synthetase by limited digestion with trypsin

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Structural organization of the multifunctional animal fatty-acid synthase

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Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer

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Mammalian fatty acid synthetase is a structurally and functionally symmetrical dimer

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The malonyl/acetyltransferase and beta-ketoacyl synthase domains of the animal fatty acid synthase can cooperate with the acyl carrier protein domain of either subunit

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Differential affinity labeling of the two subunits of the homodimeric animal fatty acid synthase allows isolation of heterodimers consisting of subunits that have been independently modified

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Fatty acid synthase dimers containing catalytically active beta-ketoacyl synthase or malonyl/acetyltransferase domains in only one subunit can support fatty acid synthesis at the acyl carrier protein domains of both subunits.

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Dibromopropanone cross-linking of the phosphopantetheine and active-site cysteine thiols of the animal fatty acid synthase can occur both inter- and intrasubunit. Reevaluation of the side-by-side, antiparallel subunit model

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Fatty acid synthase: in vitro complementation of inactive mutants

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Specificity and site of action of a mammary gland thioesterase which releases acyl moieties from thioester linkage to the fatty acid synthetase

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Purification and some properties of a medium-chain acyl-thioester hydrolase from lactating-rabbit mammary gland which terminates chain elongation in fatty acid synthesis

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Involvement of a thioesterase in the production of short-chain fatty acids in the uropygial glands of mallard ducks (Anas platyrhynchos)

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Human fatty acid synthase: assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity

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Purification and properties of fatty acid synthetase from a human breast cell line

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Expression in Escherichia coli, purification and characterization of two mammalian thioesterases involved in fatty acid synthesis

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Derived amino acid sequence and identification of active site residues of Escherichia coli beta-hydroxydecanoyl thioester dehydrase

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Site-directed mutagenesis studies on the recombinant thioesterase domain of chicken fatty acid synthase expressed in Escherichia coli

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Identifiers

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Consolidated OpenCitations Corpus – April 2017

370233

370233

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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