Pharmacological strategies to decrease transfusion requirements in patients undergoing surgery (Q28193941)

The hemostatic effects of desmopressin on patients who had total joint arthroplasty. A double-blind randomized trial

Europe PubMed Central

title

Pharmacological strategies to decrease transfusion requirements in patients undergoing surgery (English)

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Robert J Porte

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Frank W G Leebeek

series ordinal

2

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language of work or name

English

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publication date

2002

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published in

Drugs

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volume

62

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issue

15

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page(s)

2193-211

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cites work

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Hemostasis defects associated with cardiac surgery, prosthetic devices, and other extracorporeal circuits

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A prospective, randomized, double-blind trial of the use of fibrin sealant for face lifts

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Tranexamic acid reduces red cell transfusion better than epsilon-aminocaproic acid or placebo in liver transplantation

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A trial of desmopressin (1-desamino-8-D-arginine vasopressin) to reduce blood loss in uncomplicated cardiac surgery.

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Prophylactic use of tranexamic acid and incidence of arterial thrombosis in liver transplantation

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Randomized trial of fibrin adhesive for reduction of drained secretion after elective cholecystectomy

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Nafamostat mesilate administration during cardiopulmonary bypass decreases postoperative bleeding after cardiac surgery

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Aprotinin decreases blood loss in patients undergoing revision or bilateral total hip arthroplasty.

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12 December 2020

Tranexamic acid reduces blood loss, transfusion requirements, and coagulation factor use in primary orthotopic liver transplantation.

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Simultaneous occurrence of human antibodies directed against fibrinogen, thrombin, and factor V following exposure to bovine thrombin: effects on blood coagulation, protein C activation and platelet function

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Aprotinin decreases exposure to allogeneic blood during primary unilateral total hip replacement.

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A prospective, randomized study of the effects of prostacyclin on platelets and blood loss during coronary bypass operations

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Safety and efficacy of recombinant factor VIIa in patients with liver disease undergoing laparoscopic liver biopsy

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Aprotinin in peripheral vascular surgery

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Tranexamic acid: a review of its use in surgery and other indications

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Influence of desmopressin acetate on homologous blood requirements in cardiac surgical patients pretreated with aspirin

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Does desmopressin acetate prophylaxis reduce blood loss after valvular heart operations? A randomized, double-blind study

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1-Deamino-8-d-arginine vasopressin: a new pharmacological approach to the management of haemophilia and von Willebrands' diseases

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The antithrombotic effect of aprotinin: actions mediated via the proteaseactivated receptor 1

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Influence of high-dose aprotinin on anticoagulation, heparin requirement, and celite- and kaolin-activated clotting time in heparin-pretreated patients undergoing open-heart surgery. A double-blind, placebo-controlled study

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Tranexamic acid in off-pump coronary surgery: a preliminary, randomized, double-blind, placebo-controlled study.

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Tranexamic acid reduces blood loss and transfusion in reoperative cardiac surgery.

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Effect of aprotinin on need for blood transfusion after repeat open-heart surgery

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12 December 2020

Conjugated estrogen reduces transfusion and coagulation factor requirements in orthotopic liver transplantation

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12 December 2020

Does desmopressin improve hemostasis and reduce blood loss from aortic surgery? A randomized, double-blind study

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Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty

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12 December 2020

Use of desmopressin acetate to reduce blood transfusion requirements during cardiac surgery in patients with acetylsalicylic-acid-induced platelet dysfunction

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Fibrin sealant: a review of its use in surgery and endoscopy

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The use of technologies to minimize exposure to perioperative allogeneic blood transfusion in elective surgery. A survey of Canadian hospitals.

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Continuous small-dose tranexamic acid reduces fibrinolysis but not transfusion requirements during orthotopic liver transplantation

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Systematic review of the use of fibrin sealant to minimize perioperative allogeneic blood transfusion.

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Treatment of a severely bleeding patient without preexisting coagulopathy with activated recombinant factor VII

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Does desmopressin acetate reduce blood loss after surgery in patients on cardiopulmonary bypass?

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The effect of prophylactic epsilon-aminocaproic acid on bleeding, transfusions, platelet function, and fibrinolysis during coronary artery bypass grafting

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Haemostasis during transvesical prostatic adenomectomy. A controlled trial on the effect of drugs with antifibrinolytic and thrombin-like activities

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Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints

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Successful use of recombinant factor VIIa in patient with severe haemophilia A during synovectomy

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Low-dose postoperative aprotinin reduces mediastinal drainage and blood product use in patients undergoing primary coronary artery bypass grafting who are taking aspirin: a prospective, randomized, double-blind, placebo-controlled trial

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Combined fresh frozen plasma with recombinant factor VIIa in restoring hemostasis for invasive procedures in children with liver diseases

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12 December 2020

Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations

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12 December 2020

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Effect of aprotinin (Trasylol) on aorta-coronary bypass graft patency

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Analyses of coronary graft patency after aprotinin use: results from the International Multicenter Aprotinin Graft Patency Experience (IMAGE) trial.

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Dental extractions in patients with bleeding disorders. The use of fibrin glue

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12 December 2020

Aprotinin administration and pulmonary thromboembolism during orthotopic liver transplantation: report of two cases.

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12 December 2020

Aprotinin and transfusion requirements in orthotopic liver transplantation: a multicentre randomised double-blind study. EMSALT Study Group

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12 December 2020

Desmopressin usage in elective cardiac surgery

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12 December 2020

Effect of nafamostat mesilate on coagulation and fibrinolysis in hepatic resection

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12 December 2020

Does prophylactic epsilon-aminocaproic acid improve blood loss and coagulation in liver transplantation?

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12 December 2020

Clinical evaluation of a new synthetic protease inhibitor in open heart surgery. Effect on plasma serotonin and histamine release and blood conservation

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12 December 2020

The prevention of secondary haemorrhage after prostatectomy: the value of antifibrinolytic therapy

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12 December 2020

Aprotinin versus placebo in major orthopedic surgery: a randomized, double-blinded, dose-ranging study.

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12 December 2020

Tranexamic acid is effective in decreasing postoperative bleeding and transfusions in primary coronary artery bypass operations: a double-blind, randomized, placebo-controlled trial

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12 December 2020

Comparison of epsilon aminocaproic acid and normal saline for postoperative bladder irrigation following transurethral resection of prostate

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12 December 2020

The effect of aprotinin on renal function in orthotopic liver transplantation

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12 December 2020

Aprotinin decreases blood loss and homologous transfusions in patients undergoing major orthopedic surgery.

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12 December 2020

Reduced transfusion requirements by recombinant factor VIIa in orthotopic liver transplantation: a pilot study.

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12 December 2020

Hyponatremia and seizures after intravenous administration of desmopressin acetate for surgical hemostasis

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12 December 2020

Continuous infusion of recombinant factor VIIa: continue or not?

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12 December 2020

An effective treatment of severe intractable bleeding after valve repair by one single dose of activated recombinant factor VII

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12 December 2020

Reduced need for vasopressors in patients receiving aprotinin during orthotopic liver transplantation

1 reference

12 December 2020

Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.

1 reference

12 December 2020

1-Desamino-8-D-arginine vasopressin (desmopressin) decreases operative blood loss in patients having Harrington rod spinal fusion surgery. A randomized, double-blinded, controlled trial

1 reference

12 December 2020

Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin

1 reference

12 December 2020

A comparative study of the postoperative allogeneic blood-sparing effect of tranexamic acid versus acute normovolemic hemodilution after total knee replacement.

1 reference

12 December 2020

Is epsilon-aminocaproic acid as effective as aprotinin in reducing bleeding with cardiac surgery?: a meta-analysis

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12 December 2020

Aprotinin: an update of its pharmacology and therapeutic use in open heart surgery and coronary artery bypass surgery

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12 December 2020

Detrimental effects of perioperative blood transfusion.

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12 December 2020

Aprotinin reduces red blood cell transfusion in orthotopic liver transplantation: a prospective, randomized, double-blind study

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12 December 2020

Aprotinin reduces blood loss and the need for transfusion in orthognathic surgery.

1 reference

12 December 2020

Attenuation of neurologic injury during cardiac surgery

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12 December 2020

Effect of aprotinin on intraoperative bleeding and fibrinolysis in liver transplantation

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12 December 2020

1 reference

12 December 2020

Successful use of recombinant FVIIa (Novoseven) in the management of intractable post-surgical intra-abdominal haemorrhage

1 reference

12 December 2020

Aprotinin reduces postoperative bleeding and the need for blood products in thoracic surgery: results of a randomized double-blind study

1 reference

12 December 2020

The effect of desmopressin acetate on postoperative hemorrhage in patients receiving aspirin therapy before coronary artery bypass operations

1 reference

12 December 2020

Reduced blood loss by aprotinin in thoracic surgical operations associated with high risk of bleeding. A placebo-controlled, randomized phase IV study

1 reference

12 December 2020

Clinical experience with recombinant factor VIIa in patients with thrombocytopenia

1 reference

12 December 2020

Prevention of postbypass bleeding with tranexamic acid and epsilon-aminocaproic acid.

1 reference

12 December 2020

Fibrin sealant in preclinical and clinical studies

1 reference

12 December 2020

Recombinant factor VIIa corrects prothrombin time in cirrhotic patients: a preliminary study

1 reference

12 December 2020

Hemostatic effects of tranexamic acid in elective thoracic aortic surgery: a prospective, randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

Blood loss and safety with desmopressin or placebo during aorto-iliac graft surgery

1 reference

12 December 2020

Aprotinin in perspective

1 reference

12 December 2020

The prophylactic effect of aprotinin on intraoperative bleeding in liver transplantation: a randomized clinical study.

1 reference

12 December 2020

A comparative study of the postoperative allogeneic blood-sparing effects of tranexamic acid and of desmopressin after total knee replacement

1 reference

12 December 2020

A study of a weight-adjusted aprotinin dosing schedule during cardiac surgery

1 reference

12 December 2020

Efficacy of recombinant factor VIIa administered by continuous infusion to haemophilia patients with inhibitors

1 reference

12 December 2020

Use of fibrin sealant to reduce bloody drainage and hemoglobin loss after total knee arthroplasty: a brief note on a randomized prospective trial

1 reference

12 December 2020

Aprotinin in orthotopic liver transplantation: evidence for a prohemostatic, but not a prothrombotic, effect

1 reference

12 December 2020

Treatment with desmopressin acetate to reduce blood loss after cardiac surgery. A double-blind randomized trial

1 reference

12 December 2020

Successful treatment with recombinant factor VIIa of therapy-resistant severe bleeding in a patient with acquired von Willebrand disease

1 reference

12 December 2020

Elective surgery on factor VIII inhibitor patients using continuous infusion of recombinant activated factor VII: plasma factor VII activity of 10 IU/ml is associated with an increased incidence of bleeding

1 reference

12 December 2020

Prospective, randomised trial of two doses of rFVIIa (NovoSeven) in haemophilia patients with inhibitors undergoing surgery

1 reference

12 December 2020

Relationship between factor VII activity and clinical efficacy of recombinant factor VIIa given by continuous infusion to patients with factor VIII inhibitors.

1 reference

12 December 2020

Postoperatively administered aprotinin or epsilon aminocaproic acid after cardiopulmonary bypass has limited benefit

1 reference

12 December 2020

Technologies to minimize blood transfusion in cardiac and orthopedic surgery. Results of a practice variation survey in nine countries. International Study of Peri-operative Transfusion (ISPOT) Investigators

1 reference

12 December 2020

Use of point-of-care test in identification of patients who can benefit from desmopressin during cardiac surgery: a randomised controlled trial

1 reference

12 December 2020

Aprotinin and vein graft occlusion--the controversy continues

1 reference

12 December 2020

Nafamostat mesilate reduces blood loss during open heart surgery.

1 reference

12 December 2020

High-dose aprotinin therapy: a review of the first five years' experience

1 reference

12 December 2020

A polymeric sealant inhibits anastomotic suture hole bleeding more rapidly than gelfoam/thrombin: results of a randomized controlled trial

1 reference

12 December 2020

Significant merits of a fibrin sealant in the presence of coagulopathy following paediatric cardiac surgery: randomised controlled trial.

1 reference

12 December 2020

Possible mechanisms of allogeneic blood transfusion-associated postoperative infection

1 reference

12 December 2020

Tranexamic acid reduces blood loss in total hip replacement surgery

1 reference

12 December 2020

Comparison of topical hemostatic agents in elective hepatic resection: a clinical prospective randomized trial

1 reference

12 December 2020

Effects of desmopressin on blood loss in hip arthroplasty. Controlled study in 50 patients.

1 reference

12 December 2020

Continuous infusion therapy in haemophilia

1 reference

12 December 2020

Reduction of blood loss and transfusion requirement by aprotinin in posterior lumbar spine fusion

1 reference

12 December 2020

The effect of prostacyclin infusion on platelet hemostatic function in patients undergoing cardiopulmonary bypass

1 reference

12 December 2020

Metaanalysis of prophylactic drug treatment in the prevention of postoperative bleeding.

1 reference

12 December 2020

Effects of Deamino-8-D-Arginin Vasopressin on Blood Loss and Coagulation Factors in Scoliosis Surgery

1 reference

12 December 2020

Randomized clinical trial of fibrin sealant in patients undergoing resternotomy or reoperation after cardiac operations. A multicenter study

1 reference

12 December 2020

Aprotinin reduces blood loss in patients undergoing elective liver resection

1 reference

12 December 2020

Desmopressin does not reduce bleeding and transfusion requirements in congenital heart operations

1 reference

12 December 2020

Recombinant factor VIIa is effective for bleeding and surgery in patients with Glanzmann thrombasthenia

1 reference

12 December 2020

Acute myocardial infarction following administration of recombinant activated factor VII (Novo Seven) in a patient with haemophilia A and inhibitor

1 reference

12 December 2020

Disadvantages of prostacyclin infusion during cardiopulmonary bypass: a double-blind study of 50 patients having coronary revascularization

1 reference

12 December 2020

Recombinant factor VIIa in severe uremic bleeding

1 reference

12 December 2020

The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery.

1 reference

12 December 2020

Aprotinin reduces blood loss in lung transplant recipients

1 reference

12 December 2020

Effects of nafamostat mesilate on platelets and coagulofibrinolysis during cardiopulmonary bypass surgery

1 reference

12 December 2020

Hemostasis in liver transplantation

1 reference

12 December 2020