The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis (Q28195442)

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scientific article (publication date: 2006)

Language	Label	Description	Also known as
English	The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis	scientific article (publication date: 2006)

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scholarly article

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The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis (English)

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1

object named as

Pnina Fishman

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author name string

Sara Bar-Yehuda

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Lea Madi

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Lea Rath-Wolfson

4

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Avivit Ochaion

5

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Shira Cohen

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Ehud Baharav

7

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language of work or name

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publication date

2006

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Arthritis Research and Therapy

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8

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1

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R33

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International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

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20 March 2017

Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis

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20 March 2017

An agonist to the A3 adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3 beta and NF-kappa B.

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29 September 2017

Targeting I kappa B kinase for the treatment of inflammatory and other disorders

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29 September 2017

Inhibition of primary colon carcinoma growth and liver metastasis by the A3 adenosine receptor agonist CF101

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29 September 2017

Clinical pharmacology of selective COX-2 inhibitors

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29 September 2017

The role of apoptosis in rheumatoid arthritis

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29 September 2017

Pharmacology and therapeutic applications of A3 receptor subtype

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29 September 2017

Regulation of cytokine signaling and inflammation

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29 September 2017

Phosphatidylinositol-3 kinase dependent pathways: the role in control of cell growth, survival, and malignant transformation.

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29 September 2017

Sites of action for future therapy: an adenosine-dependent mechanism by which aspirin retains its antiinflammatory activity in cyclooxygenase-2 and NFkappaB knockout mice

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29 September 2017

Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists

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29 September 2017

Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5'-N-ethyluronamide as A1 and A3 adenosine receptor agonists

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29 September 2017

Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice.

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29 September 2017

Activation of adenosine A3 receptors on macrophages inhibits tumor necrosis factor-alpha

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

29 September 2017

Adenosine, an endogenous anti-inflammatory agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

29 September 2017

Tolerability, pharmacokinetics and concentration-dependent hemodynamic effects of oral CF101, an A3 adenosine receptor agonist, in healthy young men.

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2 June 2018

Involvement of phosphatidylinositol 3-kinase gamma in neutrophil apoptosis

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2 June 2018

Aspirin inhibits tumor necrosis factoralpha gene expression in murine tissue macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

2 June 2018

Antiinflammatory effect of A3 adenosine receptor agonists in murine autoimmune arthritis models.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Upregulation of A2A adenosine receptor expression by TNF-alpha in PBMC of patients with CHF: a regulatory mechanism of inflammation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Akt is an endogenous inhibitor toward tumor necrosis factor-related apoptosis inducing ligand-mediated apoptosis in rheumatoid synovial cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Targeting the A3 adenosine receptor for cancer therapy: inhibition of prostate carcinoma cell growth by A3AR agonist

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

A3 adenosine receptor activation in melanoma cells: association between receptor fate and tumor growth inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Inhibition of neutrophil apoptosis by type 1 IFN depends on cross-talk between phosphoinositol 3-kinase, protein kinase C-delta, and NF-kappa B signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide, is protective in two murine models of colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3β, and induction of the mitochondrial-dependent intrinsic caspase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Adenosine up-regulates cyclooxygenase-2 in human granulocytes: impact on the balance of eicosanoid generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Regulation of tumor necrosis factor alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526584

27 November 2018

Reversal of the antiinflammatory effects of methotrexate by the nonselective adenosine receptor antagonists theophylline and caffeine: evidence that the antiinflammatory effects of methotrexate are mediated via multiple adenosine receptors in rat ad

1 reference

https://pubmed.ncbi.nlm.nih.gov/16507132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-inflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/16507132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16507132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma up-regulates the A2B adenosine receptor expression in macrophages: a mechanism of macrophage deactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16507132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate suppresses the interleukin-6 induced generation of reactive oxygen species in the synoviocytes of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16507132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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