Signaling through focal adhesion kinase (Q28198051)

Progress in Biophysics and Molecular Biology

Europe PubMed Central

title

Signaling through focal adhesion kinase (English)

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author name string

D D Schlaepfer

series ordinal

1

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C R Hauck

series ordinal

2

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D J Sieg

series ordinal

3

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language of work or name

English

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publication date

1999

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published in

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volume

71

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page(s)

435-78

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issue

3-4

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cites work

Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Differential effects of platelet-derived growth factor BB on p125 focal adhesion kinase and paxillin tyrosine phosphorylation and on cell migration in rabbit aortic vascular smooth muscle cells and Swiss 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Gelsolin is a downstream effector of rac for fibroblast motility

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Physical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fyn

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Requirement of integrin beta3 tyrosine 747 for beta3 tyrosine phosphorylation and regulation of alphavbeta3 avidity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Src and Ras are involved in separate pathways in epithelial cell scattering

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Casting light on focal adhesions.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cloning of focal adhesion kinase, pp125FAK, from rat brain reveals multiple transcripts with different patterns of expression

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Alternatively spliced focal adhesion kinase in rat brain with increased autophosphorylation activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesions, contractility, and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Prolactin stimulates the JAK2 and focal adhesion kinase pathways in human breast carcinoma T47-D cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

c-Src is required for stimulation of gelsolin-associated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Geometric control of cell life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Interaction of focal adhesion kinase with cytoskeletal protein talin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-mediated signals regulated by members of the rho family of GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

BCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with Crkl

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Regulation of a neuronal form of focal adhesion kinase by anandamide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Control of adhesion-dependent cell survival by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cholecystokinin-stimulated tyrosine phosphorylation of p125FAK and paxillin is mediated by phospholipase C-dependent and -independent mechanisms and requires the integrity of the actin cytoskeleton and participation of p21rho

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin signaling: specificity and control of cell survival and cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Role of focal adhesion kinase in integrin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Stretching mesangial cells stimulates tyrosine phosphorylation of focal adhesion kinase pp125FAK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Reconstitution of high affinity IgE receptor-mediated secretion by transfecting protein tyrosine kinase pp125FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Molecular analysis and developmental expression of the focal adhesion kinase pp125FAK in Xenopus laevis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine phosphorylation of the related adhesion focal tyrosine kinase in megakaryocytes upon stem cell factor and phorbol myristate acetate stimulation and its association with paxillin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Csk suppression of Src involves movement of Csk to sites of Src activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion kinase is not essential for in vitro and in vivo differentiation of ES cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Identification of an Efs isoform that lacks the SH3 domain and chromosomal mapping of human Efs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Fluoroaluminate induces activation and association of Src and Pyk2 tyrosine kinases in osteoblastic MC3T3-E1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Lymphocyte antigen receptor activation of a focal adhesion kinase-related tyrosine kinase substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynamin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Regulation of cell motility by mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion kinase expression in oral cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cell migration: a physically integrated molecular process

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Outside-in integrin signal transduction. Alpha IIb beta 3-(GP IIb IIIa) tyrosine phosphorylation induced by platelet aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamellipodial advance

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Paxillin is tyrosine-phosphorylated by and preferentially associates with the calcium-dependent tyrosine kinase in rat liver epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Leupaxin is a novel LIM domain protein that forms a complex with PYK2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Protein tyrosine phosphatase 1B negatively regulates integrin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cytokine signaling through the novel tyrosine kinase RAFTK in Kaposi's sarcoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-mediated activation of focal adhesion kinase is independent of focal adhesion formation or integrin activation. Studies with activated and inhibitory beta3 cytoplasmic domain mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cytotoxic T lymphocytes express a beta3 integrin which can induce the phosphorylation of focal adhesion kinase and the related PYK-2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

K-252a induces tyrosine phosphorylation of the focal adhesion kinase and neurite outgrowth in human neuroblastoma SH-SY5Y cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrins, adhesion and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Requirements for localization of p130cas to focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Pp125FAK is required for stretch dependent morphological response of endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Interaction of two proline-rich sequences of cell adhesion kinase beta with SH3 domains of p130Cas-related proteins and a GTPase-activating protein, Graf

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Activation of protein-tyrosine kinase Pyk2 is downstream of Syk in FcepsilonRI signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Entamoeba histolytica: involvement of pp125FAK in collagen-induced signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion kinase is abundant in developing blood vessels and elevation of its phosphotyrosine content in vascular smooth muscle cells is a rapid response to angiotensin II

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine phosphorylation of the novel protein-tyrosine kinase RAFTK during an early phase of platelet activation by an integrin glycoprotein IIb-IIIa-independent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

beta1-integrin cytoplasmic subdomains involved in dominant negative function

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Identification of integrin-stimulated sites of serine phosphorylation in FRNK, the separately expressed C-terminal domain of focal adhesion kinase: a potential role for protein kinase A.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Characterization of the kinase activity essential for tyrosine phosphorylation of p130Cas in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Modulation of beta1A integrin functions by tyrosine residues in the beta1 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion kinase (p125FAK) and paxillin are substrates for sphingomyelinase-induced tyrosine phosphorylation in Swiss 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Adhesion-growth factor interactions during differentiation: an integrated biological response

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Distinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Differential signaling by the focal adhesion kinase and cell adhesion kinase beta

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin signalling and tyrosine phosphorylation: just the FAKs?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrins: emerging paradigms of signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Control of cell cycle progression by fibronectin matrix architecture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Rapid recruitment of p120RasGAP and its associated protein, p190RhoGAP, to the cytoskeleton during integrin mediated cell-substrate interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cell migration: regulation of force on extracellular-matrix-integrin complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-mediated signaling events in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A suppressive role of p125FAK protein tyrosine kinase in hydrogen peroxide-induced apoptosis of T98G cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Direct association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

The role of conserved amino acid motifs within the integrin beta3 cytoplasmic domain in triggering focal adhesion kinase phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Activation of Pyk2 by stress signals and coupling with JNK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-mediated tyrosine phosphorylation of SHPS-1 and its association with SHP-2. Roles of Fak and Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-mediated signal transduction in cells lacking focal adhesion kinase p125FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Regulation of mitogen-activated protein kinase activation by the cytoplasmic domain of the alpha6 integrin subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Expression of focal adhesion kinase gene and invasive cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Cleavage of focal adhesion kinase by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Human T and B lymphocytes express a structurally conserved focal adhesion kinase, pp125FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Diphtheria toxin-mediated ablation of parietal cells in the stomach of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Tyrosine kinase cell signaling pathways of rat mesangial cells in 3-dimensional cultures: response to fetal bovine serum and platelet-derived growth factor-BB

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

A beta peptide enhances focal adhesion kinase/Fyn association in a rat CNS nerve cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Protein kinase C and F-actin are essential for stimulation of neuronal FAK tyrosine phosphorylation by G-proteins and amyloid beta protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Regulation of the cell cycle by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900052-2

7 January 2021