HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2 (Q28201997)

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8 November 2019

title

HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2 (English)

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8 November 2019

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3

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8 November 2019

author name string

A Wächtershäuser

series ordinal

1

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8 November 2019

B Akoglu

series ordinal

2

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8 November 2019

language of work or name

English

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publication date

1 July 2001

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8 November 2019

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8 November 2019

volume

22

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8 November 2019

issue

7

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8 November 2019

page(s)

1061-1067

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Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac

8 November 2019

cites work

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Lovastatin induces apoptosis in malignant mesothelioma cells.

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Cholesterol inhibition, cancer, and chemotherapy

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Regulation of the mevalonate pathway

21 January 2018

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Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

21 January 2018

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Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

21 January 2018

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Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells

21 January 2018

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The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

21 January 2018

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Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats.

21 January 2018

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Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man

21 January 2018

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Effect of short-chain fatty acids on the human colonic mucosa in vitro

21 January 2018

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Regulation of human colonic cell line proliferation and phenotype by sodium butyrate

21 January 2018

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Mediation of differentiating effects of butyrate on the intestinal cell line Caco-2 by transforming growth factor-beta 1.

21 January 2018

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PPAR-gamma is selectively upregulated in Caco-2 cells by butyrate.

21 January 2018

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Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

21 January 2018

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Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.

21 January 2018

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p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells

21 January 2018

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Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line

21 January 2018

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Cdk inhibitors: on the threshold of checkpoints and development

21 January 2018

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Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells

21 January 2018

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Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

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Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase

21 January 2018

1 reference

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Butyrate-induced differentiation of Caco-2 cells occurs independently from p27.

21 January 2018

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Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells

21 January 2018

1 reference

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Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer

21 January 2018

1 reference

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bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis

21 January 2018

1 reference

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Expression of 15-lipoxygenase by human colorectal carcinoma Caco-2 cells during apoptosis and cell differentiation

21 January 2018

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3-Hydroxy-3-methylglutaryl--coenzyme A reductase inhibitors in the treatment of hypercholesterolemia

21 January 2018

1 reference

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Reduction of serum cholesterol in heterozygous patients with familial hypercholesterolemia. Additive effects of compactin and cholestyramine

21 January 2018

1 reference

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Rationale for the luminal provision of butyrate in intestinal diseases

21 January 2018

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/CARCIN/22.7.1061

2 references

Consolidated OpenCitations Corpus – April 2017

2579064

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8 November 2019

2579064

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

2579064

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408350%20AND%20SRC:MED&resulttype=core&format=json