CEACAM1 regulates insulin clearance in liver (Q28202001)

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Khadijeh Rezaei

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Mats A Fernström

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Abraham D Lee

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Yoshiaki Kido

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Sandra K Erickson

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Sonia M Najjar

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

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language of work or name

English

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publication date

March 2002

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published in

Nature Genetics

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volume

30

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page(s)

270-6

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issue

3

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cites work

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Alpha2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor

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Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit

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Insulin-stimulated phosphorylation of recombinant pp120/HA4, an endogenous substrate of the insulin receptor tyrosine kinase

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Suppression of tumorigenicity of breast cancer cells by an epithelial cell adhesion molecule (C-CAM1): the adhesion and growth suppression are mediated by different domains

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Biliary glycoprotein, a potential human cell adhesion molecule, is down-regulated in colorectal carcinomas

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Receptor-mediated internalization of insulin. Potential role of pp120/HA4, a substrate of the insulin receptor kinase

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The differential effects of pp120 (Ceacam 1) on the mitogenic action of insulin and insulin-like growth factor 1 are regulated by the nonconserved tyrosine 1316 in the insulin receptor

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Insulin stimulates pp120 endocytosis in cells co-expressing insulin receptors

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The effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects

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Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

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Effect of pp120 on receptor-mediated insulin endocytosis is regulated by the juxtamembrane domain of the insulin receptor

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Fatty acids in the portal vein of the rat regulate hepatic insulin clearance

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Modifications of abdominal fat and hepatic insulin clearance during severe caloric restriction.

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Splanchnic insulin metabolism in obesity. Influence of body fat distribution

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Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes

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Effect of fatty acids on glucose production and utilization in man

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Role of insulin resistance in adipose tissue and liver in the pathogenesis of endogenous hypertriglyceridaemia in man

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Hepatic insulin resistance after pancreas transplantation in type I diabetes.

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Systemic venous drainage of pancreas allografts as independent cause of hyperinsulinemia in type I diabetic recipients

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Free fatty acids and pathogenesis of type 2 diabetes mellitus

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Non-esterified fatty acids and the liver: why is insulin secreted into the portal vein?

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The glucose fatty acid cycle in obesity and maturity onset diabetes mellitus

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Mechanisms modifying glucose oxidation in diabetes mellitus

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Diminished plasma free fatty acid clearance in obese subjects

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Chronic physiologic hyperinsulinemia impairs suppression of plasma free fatty acids and increases de novo lipogenesis but does not cause dyslipidemia in conscious normal rats.

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Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

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Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

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Characterization of an enhancer element in the human apolipoprotein C-III gene that regulates human apolipoprotein A-I gene expression in the intestinal epithelium

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Cloning and characterization of a functional promoter of the rat pp120 gene, encoding a substrate of the insulin receptor tyrosine kinase

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Removal of insulin by perfused rat liver: Effect of concentration

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Lack of insulin receptors affects the formation of white adipose tissue in mice. A morphometric and ultrastructural analysis

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Role of protein kinase C and tyrosine kinase activity in IFN-gamma-induced expression of the class II MHC gene

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Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

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