Plakins: a family of versatile cytolinker proteins (Q28202388)

Antibodies to high molecular weight polypeptides of desmosomes: specific localization of a class of junctional proteins in cells and tissue.

Europe PubMed Central

title

Plakins: a family of versatile cytolinker proteins (English)

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author name string

Conrad L Leung

series ordinal

1

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Kathleen J Green

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2

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Ronald K H Liem

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3

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language of work or name

English

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publication date

January 2002

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published in

Trends in Cell Biology

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volume

12

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issue

1

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page(s)

37-45

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cites work

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Molecular structure of the human desmoplakin I and II amino terminus

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Cytoskeletal components of lymphoid organs

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The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells

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7 January 2021

The function of plakophilin 1 in desmosome assembly and actin filament organization

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The amino-terminal domain of desmoplakin binds to plakoglobin and clusters desmosomal cadherin-plakoglobin complexes

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Defining the interactions between intermediate filaments and desmosomes

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Making a connection: direct binding between keratin intermediate filaments and desmosomal proteins

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7 January 2021

Two-hybrid analysis reveals fundamental differences in direct interactions between desmoplakin and cell type-specific intermediate filaments

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7 January 2021

Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks

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7 January 2021

Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly

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Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage

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7 January 2021

Mid-gestational lethality in mice lacking keratin 8

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7 January 2021

Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates

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7 January 2021

Analysis of the desmoplakin gene reveals striking conservation with other members of the plakin family of cytolinkers

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7 January 2021

Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma

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7 January 2021

Recessive mutation in desmoplakin disrupts desmoplakin-intermediate filament interactions and causes dilated cardiomyopathy, woolly hair and keratoderma

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7 January 2021

Identification of the hemidesmosomal 500 kDa protein (HD1) as plectin

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7 January 2021

The 300-kDa intermediate filament-associated protein (IFAP300) is a hamster plectin ortholog.

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7 January 2021

High molecular weight polypeptides (270,000-340,000) from cultured cells are related to hog brain microtubule-associated proteins but copurify with intermediate filaments

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7 January 2021

Distribution of plectin, an intermediate filament-associated protein, in the adult rat central nervous system.

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7 January 2021

Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton

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7 January 2021

Unusual 5' transcript complexity of plectin isoforms: novel tissue-specific exons modulate actin binding activity.

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7 January 2021

Basic amino acid residue cluster within nuclear targeting sequence motif is essential for cytoplasmic plectin-vimentin network junctions

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7 January 2021

Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding

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7 January 2021

Linking integrin alpha6beta4-based cell adhesion to the intermediate filament cytoskeleton: direct interaction between the beta4 subunit and plectin at multiple molecular sites.

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7 January 2021

Homozygous deletion mutations in the plectin gene (PLEC1) in patients with epidermolysis bullosa simplex associated with late-onset muscular dystrophy

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7 January 2021

Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture

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7 January 2021

Not just scaffolding: plectin regulates actin dynamics in cultured cells

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7 January 2021

The BPAG1 locus: Alternative splicing produces multiple isoforms with distinct cytoskeletal linker domains, including predominant isoforms in neurons and muscles

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7 January 2021

The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1.

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7 January 2021

An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments.

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7 January 2021

Integrators of the cytoskeleton that stabilize microtubules

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7 January 2021

The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome

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7 January 2021

The intermediate filament protein peripherin is the specific interaction partner of mouse BPAG1-n (dystonin) in neurons

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7 January 2021

Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration

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7 January 2021

Dystonin Is Essential for Maintaining Neuronal Cytoskeleton Organization.

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7 January 2021

Dystonin-deficient mice exhibit an intrinsic muscle weakness and an instability of skeletal muscle cytoarchitecture

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7 January 2021

Novel actin crosslinker superfamily member identified by a two step degenerate PCR procedure

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7 January 2021

Microtubule actin cross-linking factor (MACF): a hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons

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7 January 2021

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

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7 January 2021

An epidermal plakin that integrates actin and microtubule networks at cellular junctions

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7 January 2021

kakapo, a gene required for adhesion between and within cell layers in Drosophila, encodes a large cytoskeletal linker protein related to plectin and dystrophin

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7 January 2021

short stop is allelic to kakapo, and encodes rod-like cytoskeletal-associated proteins required for axon extension.

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7 January 2021

Genes that control neuromuscular specificity in Drosophila.

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7 January 2021

Mutations that affect the length, fasciculation, or ventral orientation of specific sensory axons in the Drosophila embryo

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7 January 2021

Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis

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7 January 2021

Participation of membrane-associated proteins in the formation of the cross-linked envelope of the keratinocyte

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902180-8

7 January 2021

Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902180-8

7 January 2021

Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902180-8

7 January 2021

Subcellular distribution of envoplakin and periplakin: insights into their role as precursors of the epidermal cornified envelope

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7 January 2021

Initiation of assembly of the cell envelope barrier structure of stratified squamous epithelia

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7 January 2021

Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope

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7 January 2021

Gene targeting of envoplakin, a cytoskeletal linker protein and precursor of the epidermal cornified envelope

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7 January 2021

Antibodies against desmoglein 3 (pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902180-8

7 January 2021

Identification of a 450-kDa human epidermal autoantigen as a new member of the plectin family

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902180-8

7 January 2021

Epiplakin, a novel member of the Plakin family originally identified as a 450-kDa human epidermal autoantigen. Structure and tissue localization

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902180-8

7 January 2021