A complex containing PBX2 contributes to activation of the proto-oncogene HOX11 (Q28203462)

RNA polymerase II transcription regulatory region sequence-specific DNA binding

GOA release 2020-03-11

1 reference

Biochemical and Biophysical Research Communications

GOA release 2020-03-11

author name string

R L Brake

series ordinal

1

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U R Kees

series ordinal

2

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P M Watt

series ordinal

3

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language of work or name

English

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publication date

31 May 2002

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published in

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volume

294

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issue

1

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page(s)

23-34

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cites work

Fine mapping of human HOX gene clusters

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The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes

7 January 2021

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A Drosophila melanogaster homologue of the T-cell oncogene HOX11 localises to a cluster of homeobox genes.

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Hox11 acts cell autonomously in spleen development and its absence results in altered cell fate of mesenchymal spleen precursors

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Hox11 controls the genesis of the spleen

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HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

7 January 2021

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The t(10;14)(q24;q11) of T-cell acute lymphoblastic leukemia juxtaposes the delta T-cell receptor with TCL3, a conserved and activated locus at 10q24.

7 January 2021

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

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PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1

7 January 2021

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Pbx4, a new Pbx family member on mouse chromosome 8, is expressed during spermatogenesis

7 January 2021

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lazarus is a novel pbx gene that globally mediates hox gene function in zebrafish

7 January 2021

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A novel pbx family member expressed during early zebrafish embryogenesis forms trimeric complexes with Meis3 and Hoxb1b.

7 January 2021

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7 January 2021

New motif in PBX genes

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Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

7 January 2021

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Prep1, a novel functional partner of Pbx proteins.

7 January 2021

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Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex

7 January 2021

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A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

7 January 2021

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Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

7 January 2021

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Multiple negative elements contribute to repression of the HOX11 proto-oncogene

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Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

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HEL Cells: A New Human Erythroleukemia Cell Line with Spontaneous and Induced Globin Expression

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Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation

7 January 2021

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Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx.

7 January 2021

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HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900426-6

TALE homeoproteins as HOX11-interacting partners in T-cell leukemia

7 January 2021

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The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain

7 January 2021

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Members of the meis1 and pbx homeodomain protein families cooperatively bind a cAMP-responsive sequence (CRS1) from bovine CYP17

7 January 2021

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An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900426-6

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900426-6

Cooperative interactions between PBX, PREP, and HOX proteins modulate the activity of the alpha 2(V) collagen (COL5A2) promoter

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900426-6

The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900426-6

Two forms of Hox11 a T cell leukemia oncogene, are expressed in fetal spleen but not in primary lymphocytes.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900426-6