The many roles of cytochrome b5 (Q28206247)

Pharmacology & Therapeutics

Europe PubMed Central

title

The many roles of cytochrome b5 (English)

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author name string

John B Schenkman

series ordinal

1

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Ingela Jansson

series ordinal

2

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language of work or name

English

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publication date

February 2003

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published in

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volume

97

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page(s)

139-52

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issue

2

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cites work

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Cofactor requirements of the O-demethylating liver microsomal enzyme system

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Electron shuttle between membrane-bound cytochrome P450 3A4 and b5 rules uncoupling mechanisms

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Interactions between cytochrome P450 and cytochrome b5.

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Influence of ionic strength on the P450 monooxygenase reaction and role of cytochrome b5 in the process

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The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein

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Reconstitution of hepatic microsomal stearoyl-coenzyme A desaturase system from solubilized components

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Carbon tetrachloride changes the activity of cytochrome P450 system in the liver of male rats: role of antioxidants

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7 January 2021

Coupling of spin, substrate, and redox equilibriums in cytochrome P450

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Spin state control of the hepatic cytochrome P450 redox potential

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Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex

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A Hemochromogen Component of Liver Microsomes

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The intracellular distribution of cytochrome components and of oxidative enzyme activity in rat liver

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Purification and properties of rat liver microsomal stearyl coenzyme A desaturase

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NADH- and NADPH-dependent reconstituted p-nitroanisole O-demethylation system containing cytochrome P-450 with high affinity for cytochrome b5

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7 January 2021

Interaction and electron transfer between cytochrome b5 and cytochrome P-450 in the reconstituted p-nitroanisole O-demethylase system

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7 January 2021

Mechanism of interaction between cytochromes P-450 RLM5 and b5: evidence for an electrostatic mechanism involving cytochrome b5 heme propionate groups

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Purification to homogeneity and enzymological characterization of a functional covalent complex composed of cytochromes P-450 isozyme 2 and b5 from rabbit liver

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Differences in the spectral interactions between NADPH-cytochrome P-450 reductase and a series of cytochrome P-450 enzymes.

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Evidence of binary complex formations between cytochrome P-450, cytochrome b5, and NADPH-cytochrome P-450 reductase of hepatic microsomes

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Modulation of the reductive metabolism of halothane by microsomal cytochrome b5 in rat liver

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Cytochrome b5, its functions, structure and membrane topology

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Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.

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Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

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Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes

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Roles of Cytochrome b5in the Oxidation of Testosterone and Nifedipine by Recombinant Cytochrome P450 3A4 and by Human Liver Microsomes

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Stimulation of cytochrome P450 reactions by apo-cytochrome b5: evidence against transfer of heme from cytochrome P450 3A4 to apo-cytochrome b5 or heme oxygenase

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

565690

565690

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference