Model for the three-dimensional structure of vitronectin: predictions for the multi-domain protein from threading and docking (Q28206585)

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K Baburaj

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C B Peterson

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Y Xu

Structure and Biological Role of Vitronectin

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language of work or name

English

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publication date

15 August 2001

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published in

Proteins

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volume

44

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issue

3

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page(s)

312-20

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cites work

1 reference

21 January 2018

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin

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Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

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Multiple interactions between human vitronectin and Staphylococcus aureus

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The hemopexin-type repeats of human vitronectin are recognized by Streptococcus pyogenes

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Identification of novel heparin-binding domains of vitronectin

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Prediction of protein secondary structure at better than 70% accuracy

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The cluster of basic amino acids in vitronectin contributes to its binding of plasminogen activator inhibitor-1: evidence from thrombin-, elastase- and plasmin-cleaved vitronectins and anti-peptide antibodies

21 January 2018

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Vitronectin-mediated inhibition of complement: evidence for different binding sites for C5b-7 and C9

21 January 2018

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Endogenous cleavage of the Arg-379-Ala-380 bond in vitronectin results in a distinct conformational change which ‘buries’ Ser-378, its site of phosphorylation by protein kinase A

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An efficient computational method for globally optimal threading.

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Protein threading by PROSPECT: a prediction experiment in CASP3.

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Characterization of human S protein, an inhibitor of the membrane attack complex of complement. Demonstration of a free reactive thiol group

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Mapping the protein universe

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Dictionary of recurrent domains in protein structures

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Comparative protein modelling by satisfaction of spatial restraints

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Low-resolution docking: prediction of complexes for underdetermined structures.

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N.m.r. and molecular-modelling studies of the solution conformation of heparin

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VMD: visual molecular dynamics

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Arrangement of disulfide bridges and positions of sulfhydryl groups in tetanus toxin

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Saturated BLAST: an automated multiple intermediate sequence search used to detect distant homology.

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GenTHREADER: an efficient and reliable protein fold recognition method for genomic sequences

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MODBASE, a database of annotated comparative protein structure models

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WHAT IF: a molecular modeling and drug design program

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PROCHECK: a program to check the stereochemical quality of protein structures

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Structural analysis based on state-space modeling

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Characterization of the ligand binding activities of vitronectin: interaction of vitronectin with lipids and identification of the binding domains for various ligands using recombinant domains

21 January 2018

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Evidence for a specific interaction of vitronectin with arginine: effects of reducing agents on the expression of functional domains and immunoepitopes

21 January 2018

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Tachylectin-2: crystal structure of a specific GlcNAc/GalNAc-binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus

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Beta propellers: structural rigidity and functional diversity

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An extracellular beta-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components

21 January 2018

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The heparin binding domain of S-protein/vitronectin binds to complement components C7, C8, and C9 and perforin from cytolytic T-cells and inhibits their lytic activities

21 January 2018

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The use of fluorescent probes to characterize conformational changes in the interaction between vitronectin and plasminogen activator inhibitor-1

21 January 2018

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Activation of the collagen-binding of endogenous serum vitronectin by heating, urea and glycosaminoglycans

21 January 2018

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Specific binding of plasminogen to vitronectin. Evidence for a modulatory role of vitronectin on fibrin(ogen)-induced plasmin formation by tissue plasminogen activator

21 January 2018

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Synthetic peptides derived from the sequence around the plasmin cleavage site in vitronectin. Use in mapping the PAI-1 binding site

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1 reference

Characterization of the denaturation and renaturation of human plasma vitronectin. I. Biophysical characterization of protein unfolding and multimerization

21 January 2018

1 reference

Characterization of the denaturation and renaturation of human plasma vitronectin. II. Investigation into the mechanism of formation of multimers

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1 reference

Sequence location of a putative transglutaminase cross-linking site in human vitronectin

21 January 2018

1 reference

Orientation of heparin-binding sites in native vitronectin. Analyses of ligand binding to the primary glycosaminoglycan-binding site indicate that putative secondary sites are not functional

21 January 2018

1 reference

Kinetic analysis of the interaction between type 1 plasminogen activator inhibitor and vitronectin and evidence that the bovine inhibitor binds to a thrombin-derived amino-terminal fragment of bovine vitronectin

21 January 2018

1 reference

Native and multimeric vitronectin exhibit similar affinity for heparin. Differences in heparin binding properties induced upon denaturation are due to self-association into a multivalent form

21 January 2018

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Structural basis of activity and subunit recognition in G protein heterotrimers

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