Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cells (Q28206601)

2

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Ginger G Wescott

3

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Daqing Wu

4

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Tonia L Foreman

5

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Christopher W Gregory

6

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Douglas A Weidner

7

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O Harris Ford

8

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A Morgan Lasater

9

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James L Mohler

10

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David M Terrian

Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrion

11

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language of work or name

English

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publication date

11 September 2003

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published in

Oncogene

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volume

22

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issue

39

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page(s)

7958-68

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cites work

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Protein kinase C isoenzyme patterns characteristically modulated in early prostate cancer

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Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation

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Protein kinase C-epsilon promotes survival of lung cancer cells by suppressing apoptosis through dysregulation of the mitochondrial caspase pathway

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Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis

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Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS

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C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP.

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Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features

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Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta

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Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCalpha

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Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.

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Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

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Bcl-2 and Bax function independently to regulate cell death

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Regulation of the expression of protein kinase C isoenzymes in rat ventral prostate: effects of age, castration and flutamide treatment

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Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling

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Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state

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14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax

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Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains

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Functional proteomic analysis of protein kinase C epsilon signaling complexes in the normal heart and during cardioprotection

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Molecular analysis of the interactions between protein kinase C-epsilon and filamentous actin

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Identification and localization of an actin-binding motif that is unique to the epsilon isoform of protein kinase C and participates in the regulation of synaptic function

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Rational design, synthesis, and biological evaluation of rigid pyrrolidone analogues as potential inhibitors of prostate cancer cell growth

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The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax

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Adaptor proteins in protein kinase C-mediated signal transduction

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Molecular conformation dictates signaling module formation: example of PKCepsilon and Src tyrosine kinase.

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Protein kinase Cdelta amplifies ceramide formation via mitochondrial signaling in prostate cancer cells

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Structure of Bax: coregulation of dimer formation and intracellular localization

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Regulation of caveolin-1 expression and secretion by a protein kinase cepsilon signaling pathway in human prostate cancer cells

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RB activation and repression of C-MYC transcription precede apoptosis of human prostate epithelial cells

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Retinoblastoma protein-dependent growth signal conflict and caspase activity are required for protein kinase C-signaled apoptosis of prostate epithelial cells

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Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals

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c-Jun N-terminal kinase mediates apoptotic signaling induced by N-(4-hydroxyphenyl)retinamide.

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Androgen receptor up-regulates insulin-like growth factor binding protein-5 (IGFBP-5) expression in a human prostate cancer xenograft

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The protein kinase C activator, phorbol ester, elicits disparate functional responses in androgen-sensitive and androgen-independent human prostatic cancer cells

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Identifiers

DOI

10.1038/SJ.ONC.1206795

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

4892077

1004146655

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4892077

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference