Functions of lumican and fibromodulin: lessons from knockout mice (Q28207266)

Europe PubMed Central

title

Functions of lumican and fibromodulin: lessons from knockout mice (English)

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Shukti Chakravarti

1

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language of work or name

English

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publication date

2002

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Expression pattern and gene characterization of asporin. a newly discovered member of the leucine-rich repeat protein family

published in

Glycoconjugate Journal

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volume

19

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issue

4-5

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page(s)

287-93

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cites work

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Fibromodulin and lumican bind to the same region on collagen type I fibrils

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Specific inhibition of type I and type II collagen fibrillogenesis by the small proteoglycan of tendon

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Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene

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Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican

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Tendon response to tensile stress: an ultrastructural investigation of collagen:proteoglycan interactions in stressed tendon

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Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22

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Structure of oligosaccharides and the linkage region between keratan sulfate and the core protein on proteoglycans from monkey cornea

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Structure and deduced amino acid sequence of the human fibromodulin gene

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Isolation and partial characterization of lumican and decorin from adult chicken corneas. A keratan sulfate-containing isoform of decorin is developmentally regulated

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Identification of the N-linked oligosaccharide sites in chick corneal lumican and keratocan that receive keratan sulfate.

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Isoforms of corneal keratan sulfate proteoglycan

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Mutations in NYX, encoding the leucine-rich proteoglycan nyctalopin, cause X-linked complete congenital stationary night blindness

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The comparative chemical morphology of the mammalian cornea.

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Cellular functions of proteoglycans--an overview.

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Molecular polymorphism of lumican during corneal development

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Super-motifs and evolution of tandem leucine-rich repeats within the small proteoglycans--biglycan, decorin, lumican, fibromodulin, PRELP, keratocan, osteoadherin, epiphycan, and osteoglycin

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Fibromodulin-null mice have abnormal collagen fibrils, tissue organization, and altered lumican deposition in tendon

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Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice

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A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice

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Localization of mouse lumican (keratan sulfate proteoglycan) to distal chromosome 10

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The effect of proteoglycans on the morphology of collagen fibrils formed in vitro

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Localization of the human fibromodulin gene (FMOD) to chromosome 1q32 and completion of the cDNA sequence

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Regulation of corneal collagen fibrillogenesis in vitro by corneal proteoglycan (lumican and decorin) core proteins

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Keratan sulfate glycosaminoglycans in murine eosinophil-specific granules

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Unique glycosylation of three keratan sulfate proteoglycan isoforms

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Mutations in corneal carbohydrate sulfotransferase 6 gene (CHST6) cause macular corneal dystrophy in Iceland

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Expression of the keratan sulfate proteoglycans lumican, keratocan and osteoglycin/mimecan during chick corneal development.

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The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins

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The structure and transparency of the cornea

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Absence of normal keratan sulfate in the blood of patients with macular corneal dystrophy

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Murine fibromodulin: cDNA and genomic structure, and age-related expression and distribution in the knee joint

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Biosynthesis of glycosaminolgycans during corneal development

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Arterial lumican. Properties of a corneal-type keratan sulfate proteoglycan from bovine aorta

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Proteoglycan changes during restoration of transparency in corneal scars

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Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons

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Immunolocalization of keratan sulphate in the human embryonic cornea and other human foetal organs

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An x-ray diffraction investigation of corneal structure in lumican-deficient mice

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Linkage of a gene for macular corneal dystrophy to chromosome 16

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