Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update (Q28207314)

Europe PubMed Central

title

Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update (English)

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main subject

uridine

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ChEBI release 2020-05-28

Giuseppe Pizzorno

1

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Deliang Cao

2

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Janine J Leffert

3

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Rosalind L Russell

4

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Dekai Zhang

5

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Robert E Handschumacher

Biochimica et Biophysica Acta

6

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language of work or name

English

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publication date

18 July 2002

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published in

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volume

1587

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issue

2-3

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page(s)

133-44

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STUDIES OF FLUORINATED PYRIMIDINES. XVIII. THE DEGRADATION OF 5-FLUORO-2'-DEOXYURIDINE AND RELATED COMPOUNDS BY NUCLEOSIDE PHOSPHORYLASE.

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Cytokines induce uridine phosphorylase in mouse colon 26 carcinoma cells and make the cells more susceptible to 5'-deoxy-5-fluorouridine.

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Species differences in substrate specificity of pyrimidine nucleoside phosphorylase

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Effects of N,N-dimethylformamide and sodium butyrate on enzymes of pyrimidine metabolism in cultured human tumor cells

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Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation

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Association of ovarian Malignancy With Expression of Paltelet-Derived Endothelial Cell Growth Factor

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Pyrimidine nucleotide metabolism in human colon carcinomas: comparison of normal tissues, primary tumors and xenografts.

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Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma

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Expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast cancer

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Angiogenic activity of enzymes.

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Identification of an additional negative regulatory region for p53 sequence-specific DNA binding

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A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

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The function of intermediate filaments in cell shape and cytoskeletal integrity

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Cytoplasmic retention of mutant tsp53 is dependent on an intermediate filament protein (vimentin) scaffold

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Copurification of vimentin, energy metabolism enzymes, and a MER5 homolog with nucleoside diphosphate kinase. Identification of tissue-specific interactions

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Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit

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Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton

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Uridine receptor: discovery and its involvement in sleep mechanism

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7 January 2021

Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder

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