Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels (Q28207513)

Europe PubMed Central

title

Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels (English)

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https://api.crossref.org/works/10.1038/SJ.ONC.1206813

18 March 2024

4

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Maria Rita Nicotra

3

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author name string

Ester Fonsatti

1

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Maresa Altomonte

2

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Michele Maio

full work available at URL

5

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language of work or name

English

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publication date

29 September 2003

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https://www.nature.com/articles/1206813.pdf

file format

Portable Document Format

online access status

open access

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Europe PubMed Central

PubMed ID

14528280

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14528280

https://www.nature.com/articles/1206813.pdf

18 March 2024

file format

Portable Document Format

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https://api.crossref.org/works/10.1038/SJ.ONC.1206813

https://www.nature.com/articles/1206813

18 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206813

18 March 2024

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22

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page(s)

6557-63

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issue

42

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cites work

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Estimation of angiogenesis with anti-CD105 immunostaining in the process of colorectal cancer development

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Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions

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Transcriptional activation of endoglin and transforming growth factor-beta signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury

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Strategies for vascular targeting in tumors

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Angiogenesis in cancer and other diseases

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Expression and function of CD105 during the onset of hematopoiesis from Flk1(+) precursors.

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Endoglin, a TGF-beta receptor-associated protein, is expressed by smooth muscle cells in human atherosclerotic plaques

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Targeting gene expression to endothelium in transgenic animals: a comparison of the human ICAM-2, PECAM-1 and endoglin promoters

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CD105 expression is a marker of high metastatic risk and poor outcome in breast carcinomas. Correlations between immunohistochemical analysis and long-term follow-up in a series of 929 patients

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Vascular attack as a therapeutic strategy for cancer

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Expression of endoglin in human mesangial cells: modulation of extracellular matrix synthesis

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Assignment of the human endoglin gene (END) to 9q34-->qter

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Cell type specificity of the human endoglin promoter

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Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells

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Endoglin expression in early development is associated with vasculogenesis and angiogenesis.

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7 January 2021

A simple analysis of gene expression and variability in gene arrays based on repeated observations

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7 January 2021

Role of angiogenesis in patients with cerebral ischemic stroke

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7 January 2021

Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen

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7 January 2021

Phosphorylation of the human-transforming-growth-factor-beta-binding protein endoglin

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7 January 2021

Endoglin, a component of the TGF-beta receptor system, is a differentiation marker of human choriocarcinoma cells

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7 January 2021

Role of endoglin in cellular responses to transforming growth factor-beta. A comparative study with betaglycan.

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7 January 2021

Plasma levels of soluble CD105 correlate with metastasis in patients with breast cancer

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7 January 2021

CD105 antagonizes the inhibitory signaling of transforming growth factor beta1 on human vascular endothelial cells

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7 January 2021

Defective angiogenesis in mice lacking endoglin

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7 January 2021

Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion

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7 January 2021

Endoglin is overexpressed after arterial injury and is required for transforming growth factor-beta-induced inhibition of smooth muscle cell migration

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7 January 2021

In vitro inhibition of endothelial cell growth by the antiangiogenic drug AGM-1470 (TNP-470) and the anti-endoglin antibody TEC-11.

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7 January 2021

Six novel mutations in the endoglin gene in hereditary hemorrhagic telangiectasia type 1 suggest a dominant-negative effect of receptor function

1 reference

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7 January 2021

Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

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7 January 2021

Elevated expression of endoglin, a component of the TGF-beta-receptor complex, correlates with proliferation of tumor endothelial cells

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7 January 2021

Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105).

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7 January 2021

Endoglin: a 180-kD endothelial cell and macrophage restricted differentiation molecule

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7 January 2021

Angiogenesis occurs in hairy cell leukaemia (HCL) and in NOD/SCID mice transplanted with the HCL line Bonna-12

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Microvessel density, a surrogate marker of angiogenesis, is significantly related to survival in multiple myeloma patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Distribution of endoglin in early human development reveals high levels on endocardial cushion tissue mesenchyme during valve formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Transcriptional targeting of conditionally replicating adenovirus to dividing endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Mechanisms and future directions for angiogenesis-based cancer therapies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Endoglin (CD105) expression in squamous cell carcinoma of the oral cavity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Expression of endoglin (CD105) in tumor blood vessels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Antiangiogenic radioimmunotherapy of human solid tumors in SCID mice using (125)I-labeled anti-endoglin monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Correlation between apoptotic index and angiogenesis in non-small cell lung cancer: comparison between CD105 and CD34 as a marker of angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Arteriovenous malformations in mice lacking activin receptor-like kinase-1

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Hereditary hemorrhagic telangiectasia: an update on transforming growth factor beta signaling in vasculogenesis and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Vascular gene transfer driven by endoglin and ICAM-2 endothelial-specific promoters.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

A monoclonal antibody detects heterogeneity in vascular endothelium of tumours and normal tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Breast carcinoma: comparative study of tumor vasculature using two endothelial cell markers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Endoglin (CD105) is expressed on immature blood vessels and is a marker for survival in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Endoglin expression on human microvascular endothelial cells association with betaglycan and formation of higher order complexes with TGF-beta signalling receptors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206813

7 January 2021

Hypoxia-induced angiogenesis during carcinogenesis

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https://api.crossref.org/works/10.1038/SJ.ONC.1206813

18 March 2024

Identifiers

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2685388

1003914418

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2685388

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference