Sex, AGility, and the regulation of alternative splicing (Q28207540)

alternative mRNA splicing, via spliceosome

Europe PubMed Central

title

Sex, AGility, and the regulation of alternative splicing (English)

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main subject

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Brenton R Graveley

1

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language of work or name

English

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publication date

17 May 2002

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published in

Cell

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volume

109

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issue

4

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page(s)

409-12

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cites work

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The RNA splicing factor hSlu7 is required for correct 3' splice-site choice

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Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45

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Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG.

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Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation.

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