p21-activated Kinase-1 Signaling Mediates Cyclin D1 Expression in Mammary Epithelial and Cancer Cells (Q28207743)

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18 March 2024

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5

Richard G Pestell

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author name string

Seetharaman Balasenthil

1

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Rui-An Wang

4

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Rakesh Kumar

7

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Aysegul A. Sahin

2

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18 March 2024

Christopher J. Barnes

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Richard G. Pestell

5

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18 March 2024

Ratna K. Vadlamudi

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language of work or name

English

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publication date

9 January 2004

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6 October 2003

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full work available at URL

18 March 2024

http://www.jbc.org/content/279/2/1422.full.pdf

file format

Portable Document Format

online access status

open access

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https://api.elsevier.com/content/article/PII:S0021925818527587?httpAccept=text/xml

18 March 2024

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https://api.elsevier.com/content/article/PII:S0021925818527587?httpAccept=text/plain

18 March 2024

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https://syndication.highwire.org/content/doi/10.1074/jbc.M309937200

18 March 2024

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Journal of Biological Chemistry

18 March 2024

published in

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volume

279

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page(s)

1422-8

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issue

2

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cites work

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

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Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

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The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

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Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis

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Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

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Emerging from the Pak: the p21-activated protein kinase family.

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Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

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Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

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Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase

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Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1

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Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma

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Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma

21 January 2018

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P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium

21 January 2018

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Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

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Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells

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Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB.

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Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

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c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry

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Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint

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A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence

21 January 2018

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Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation

21 January 2018

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Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor

21 January 2018

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Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells

21 January 2018

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RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

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Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

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p21-activated kinase 1 activates the nuclear factor kappa B (NF-kappa B)-inducing kinase-Ikappa B kinases NF-kappa B pathway and proinflammatory cytokines in Helicobacter pylori infection

21 January 2018

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CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappaB/Rel heterodimers

21 January 2018

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PRAD1/cyclin D1 proto-oncogene: genomic organization, 5' DNA sequence, and sequence of a tumor-specific rearrangement breakpoint

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Regulatable Expression of p21-activated Kinase-1 Promotes Anchorage-independent Growth and Abnormal Organization of Mitotic Spindles in Human Epithelial Breast Cancer Cells

21 January 2018

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Dysregulation of phosphatidylinositol 3-kinase and downstream effectors in human breast cancer

21 January 2018

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beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland

18 March 2024

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NDF induces expression of a novel 46 kD protein in estrogen receptor positive breast cancer cells

18 March 2024

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18 March 2024

Identifiers

1 reference

Consolidated OpenCitations Corpus – April 2017

1612599

1612599

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference