The p36 isoform of BAG-1 is translated by internal ribosome entry following heat shock (Q28211732)

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M L deSchoolmeester

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G A Fraser

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B M Pickering

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G Packham

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A E Willis

BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release.

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language of work or name

English

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publication date

5 July 2001

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published in

Oncogene

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volume

20

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page(s)

4095-100

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issue

30

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cites work

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Control of translation initiation in animals.

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A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

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Distinct isoforms of the cofactor BAG-1 differentially affect Hsc70 chaperone function.

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c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock

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Bag1 functions in vivo as a negative regulator of Hsp70 chaperone activity

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Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation

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C-Myc 5' untranslated region contains an internal ribosome entry segment

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c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis.

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Analysis of the c-myc IRES; a potential role for cell-type specific trans-acting factors and the nuclear compartment

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Characterization of interactions between the anti-apoptotic protein BAG-1 and Hsc70 molecular chaperones

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Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

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Cloning of cDNAs encoding the human BAG1 protein and localization of the human BAG1 gene to chromosome 9p12

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Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes

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Translation of CUG- but not AUG-initiated forms of human fibroblast growth factor 2 is activated in transformed and stressed cells

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Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

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Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway

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Location of the internal ribosome entry site in the 5' non-coding region of the immunoglobulin heavy-chain binding protein (BiP) mRNA: evidence for specific RNA-protein interactions

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Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells

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A protein that interacts with members of the nuclear hormone receptor family: identification and cDNA cloning

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Cap-independent translation of heat shock messenger RNAs

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inferred from DOI database lookup

7 January 2021

based on heuristic

The effect of diftalone on collagen and glycosaminoglycans metabolism

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