Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy (Q28213231)

hydrogen-ion concentration

Europe PubMed Central

title

Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy (English)

0 references

main subject

chemotherapy

0 references

1 reference

Europe PubMed Central

PubMed ID

14585264

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14585264

26 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3

26 March 2024

Yoichiro Yoshida

5

1 reference

ORCID Public Data File 2021

author name string

Hiroto Izumi

1

0 references

Takayuki Torigoe

2

0 references

Hiroshi Ishiguchi

3

0 references

Hidetaka Uramoto

4

0 references

Mizuho Tanabe

6

0 references

Tomoko Ise

7

0 references

Tadashi Murakami

8

0 references

Takeshi Yoshida

9

0 references

Minoru Nomoto

10

0 references

Kimitoshi Kohno

full work available at URL

11

0 references

language of work or name

English

0 references

publication date

December 2003

0 references

https://api.elsevier.com/content/article/PII:S0305737203001063?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3

https://api.elsevier.com/content/article/PII:S0305737203001063?httpAccept=text/plain

26 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3

Transgenic mouse models of tumour angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models

26 March 2024

published in

Cancer Treatment Reviews

0 references

volume

29

0 references

issue

6

0 references

page(s)

541-9

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

DNA methylation and breast carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

New functions for the matrix metalloproteinases in cancer progression

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

The vacuolar (H+)-ATPases--nature's most versatile proton pumps

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

beta(1) integrin binds the 16-kDa subunit of vacuolar H(+)-ATPase at a site important for human papillomavirus E5 and platelet-derived growth factor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Suppression of tumor-related glycosylation of cell surface receptors by the 16-kDa membrane subunit of vacuolar H+-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

The Sos1-Rac1 signaling. Possible involvement of a vacuolar H(+)-ATPase E subunit.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Elevated expression of vacuolar proton pump genes and cellular PH in cisplatin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

The cell biology of multiple drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Involvement of Vacuolar H+-Adenosine Triphosphatase Activity in Multidrug Resistance in HL60 Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

pH and drug resistance. I. functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

pH and drug resistance. II. turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Enhanced expression of the human vacuolar H+-ATPase c subunit gene (ATP6L) in response to anticancer agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Relation between intracellular acidification and camptothecin-induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Structure and function of vacuolar class of ATP-driven proton pumps

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Structure of a 16 kDa integral membrane protein that has identity to the putative proton channel of the vacuolar H(+)-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Inhibitory effect of modified bafilomycins and concanamycins on P- and V-type adenosinetriphosphatases.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Cell volume in the regulation of cell proliferation and apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Inhibition of Jurkat-T-lymphocyte Na+/H+-exchanger by CD95(Fas/Apo-1)-receptor stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

CD44 cell adhesion molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Mechanism and biological significance of the Ha-ras-induced activation of the Na+/H(+)-antiporter

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

The p42/p44 mitogen-activated protein kinase cascade is determinant in mediating activation of the Na+/H+ exchanger (NHE1 isoform) in response to growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

p160ROCK mediates RhoA activation of Na-H exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Na+:HCO(3-) cotransporters (NBC): cloning and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

VHL tumor suppressor regulates Cl-/HCO3- exchange and Na+/H+ exchange activities in renal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Triflocin, a novel inhibitor for the Na-HCO3 symport in the proximal tubule

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Cytostatic potential of novel agents that inhibit the regulation of intracellular pH.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Acidic environment causes apoptosis by increasing caspase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Cytotoxicity of weak electrolytes after the adaptation of cells to low pH: role of the transmembrane pH gradient

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Role of organelle pH in tumor cell biology and drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Enhancement of chemotherapy by manipulation of tumour pH.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900106-3

7 January 2021

Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH

2

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3

Hypoxia-induced enrichment and mutagenesis of cells that have lost DNA mismatch repair

26 March 2024

3

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3

A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles

26 March 2024

20

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3

Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification

26 March 2024

23

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3

Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions

26 March 2024

52

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3

Heterogeneity of intracellular pH and of mechanisms that regulate intracellular pH in populations of cultured cells

26 March 2024

60

1 reference

https://api.crossref.org/works/10.1016/S0305-7372(03)00106-3