Hereditary multiple exostoses and heparan sulfate polymerization (Q28213553)

hereditary multiple exostoses

Europe PubMed Central

title

Hereditary multiple exostoses and heparan sulfate polymerization (English)

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main subject

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Beverly M Zak

1

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Brett E Crawford

series ordinal

2

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Jeffrey D Esko

series ordinal

3

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language of work or name

English

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publication date

19 December 2002

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published in

Biochimica et Biophysica Acta

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volume

1573

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issue

3

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page(s)

346-55

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cites work

The natural history of hereditary multiple exostoses

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7 January 2021

Assignment of a second locus for multiple exostoses to the pericentromeric region of chromosome 11

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7 January 2021

A gene for hereditary multiple exostoses maps to chromosome 19p.

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7 January 2021

Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes

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7 January 2021

Genotype-phenotype correlation in hereditary multiple exostoses

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7 January 2021

Molecular dissection of a contiguous gene syndrome: localization of the genes involved in the Langer-Giedion syndrome

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7 January 2021

Order out of chaos: assembly of ligand binding sites in heparan sulfate

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7 January 2021

Molecular diversity of heparan sulfate

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7 January 2021

Proteoglycans: structures and interactions

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7 January 2021

Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry

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7 January 2021

Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans

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7 January 2021

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis

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7 January 2021

Activity of the yeast MNN1 alpha-1,3-mannosyltransferase requires a motif conserved in many other families of glycosyltransferases

1 reference

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7 January 2021

A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins

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7 January 2021

The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.

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7 January 2021

The DXD motif is required for GM2 synthase activity but is not critical for nucleotide binding

1 reference

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7 January 2021

Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Structure/function studies of glycosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Etiological point mutations in the hereditary multiple exostoses gene EXT1: a functional analysis of heparan sulfate polymerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Association of EXT1 and EXT2, hereditary multiple exostoses gene products, in Golgi apparatus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Cloning and expression of a novel, tissue specifically expressed member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

1 reference

7 January 2021

Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

N-acetylgalactosamine (GalNAc) transfer to the common carbohydrate-protein linkage region of sulfated glycosaminoglycans. Identification of UDP-GalNAc:chondro-oligosaccharide alpha-N-acetylgalactosaminyltransferase in fetal bovine serum.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Assessment of glycosaminoglycan-protein linkage tetrasaccharides as acceptors for GalNAc- and GlcNAc-transferases from mouse mastocytoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Identification and characterization of a novel UDP-GalNAc:GlcAbeta-R alpha1,4-N-acetylgalactosaminyltransferase from a human sarcoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Identification of a novel glycosaminoglycan core-like molecule. II. Alpha-GalNAc-capped xylosides can be made by many cell types

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Characterization of mammalian UDP-GalNAc:glucuronide alpha 1-4-N-acetylgalactosaminyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

alpha-N-acetylgalactosamine-capping of chondroitin sulfate core region oligosaccharides primed on xylosides

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

rib-2, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes encodes a novel alpha1,4-N-acetylglucosaminyltransferase involved in the biosynthetic initiation and elongation of heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Identification of a receptor for reg (regenerating gene) protein, a pancreatic beta-cell regeneration factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Overexpression of EXTL3/EXTR1 enhances NF-kappaB activity induced by TNF-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Biosynthesis of heparin. The D-glucuronosyl- and N-acetyl-D-glucosaminyltransferase reactions and their relation to polymer modification

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Biosynthesis of heparin. Relationship between the polymerization and sulphation processes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Functions of cell surface heparan sulfate proteoglycans

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Hormone regulation of chondrocyte differentiation and endochondral bone formation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Proteolytic processing yields two secreted forms of sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Heparan sulfate: growth control with a restricted sequence menu

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

FGF signaling in skeletal development.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Binding of heparin/heparan sulfate to fibroblast growth factor receptor 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Drosophila heparan sulfate 6-O-sulfotransferase (dHS6ST) gene. Structure, expression, and function in the formation of the tracheal system.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

Sequence analysis of heparan sulfate epitopes with graded affinities for fibroblast growth factors 1 and 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021

EXT 1 gene mutation induces chondrocyte cytoskeletal abnormalities and defective collagen expression in the exostoses

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900402-6

7 January 2021