Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN (Q28214520)

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14 December 2019

title

Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN (English)

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14 December 2019

9

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14 December 2019

author name string

Masafumi Mizuide

1

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14 December 2019

Takane Hara

2

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14 December 2019

Toshio Furuya

3

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14 December 2019

Masafumi Takeda

4

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14 December 2019

Kiyoshi Kusanagi

5

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14 December 2019

Yuri Inada

6

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14 December 2019

Masatomo Mori

7

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14 December 2019

Takeshi Imamura

8

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14 December 2019

Kohei Miyazono

10

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14 December 2019

language of work or name

English

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publication date

7 November 2002

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Journal of Biological Chemistry

14 December 2019

published in

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14 December 2019

volume

278

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issue

1

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page(s)

531-536

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Signaling of transforming growth factor-beta family members through Smad proteins

14 December 2019

cites work

1 reference

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The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

21 January 2018

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TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300

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Role of p300, a transcriptional coactivator, in signalling of TGF-beta

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Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

21 January 2018

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c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

21 January 2018

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The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

21 January 2018

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Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor

21 January 2018

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Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

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Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

21 January 2018

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TGF-beta signaling by Smad proteins

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The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization

21 January 2018

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Structural basis of Smad1 activation by receptor kinase phosphorylation

21 January 2018

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Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif

21 January 2018

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Determinants of specificity in TGF-beta signal transduction.

21 January 2018

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TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 January 2018

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The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling

21 January 2018

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Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors

21 January 2018

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Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 January 2018

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

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Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

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The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

21 January 2018

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Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control

21 January 2018

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Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling

21 January 2018

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Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells

21 January 2018

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

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Crystal Structure of a Phosphorylated Smad2

21 January 2018

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Viral ski inhibits retinoblastoma protein (Rb)-mediated transcriptional repression in a dominant negative fashion

21 January 2018

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Alpha-helix 2 in the amino-terminal mad homology 1 domain is responsible for specific DNA binding of Smad3

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C200596200

1 reference

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14 December 2019

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