Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis (Q28214768)

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scientific article (publication date: 13 September 2002)

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English	Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis	scientific article (publication date: 13 September 2002)

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scholarly article

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11 November 2019

Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis (English)

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11 November 2019

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11 November 2019

Ingemar Björkhem

11

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11 November 2019

Ingemar Björkhem

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11 November 2019

author name string

Karen Meir

1

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11 November 2019

Daniel Kitsberg

2

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11 November 2019

Irit Alkalay

3

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Fanny Szafer

4

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Haim Rosen

5

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11 November 2019

Shoshanna Shpitzen

6

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11 November 2019

Liat Ben Avi

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11 November 2019

Catherine Fievet

9

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11 November 2019

Vardiella Meiner

10

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11 November 2019

Eran Leitersdorf

13

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publication date

15 July 2002

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11 November 2019

Journal of Biological Chemistry

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277

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37

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11 November 2019

34036-34041

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11 November 2019

Low density lipoprotein (LDL) cholesterol is converted to 27-hydroxycholesterol in human fibroblasts. Evidence that 27-hydroxycholesterol can be an important intracellular mediator between LDL and the suppression of cholesterol production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

Removal of cholesterol from extrahepatic sources by oxidative mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201122200

21 January 2018

Identifiers

10.1074/JBC.M201122200

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11 November 2019

1 reference

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11 November 2019

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