The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity (Q28216093)

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scientific article (publication date: 2002)

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English	The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity	scientific article (publication date: 2002)

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6 December 2019

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity (English)

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6 December 2019

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apoptotic process

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6 December 2019

Peter Vandenabeele

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6 December 2019

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van Loo G

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6 December 2019

van Gurp M

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6 December 2019

Depuydt B

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6 December 2019

Srinivasula SM

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6 December 2019

Alnemri ES

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6 December 2019

Gevaert K

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6 December 2019

Vandekerckhove J

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6 December 2019

Declercq W

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6 December 2019

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1 January 2002

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6 December 2019

Cell Death & Differentiation

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6 December 2019

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6 December 2019

1

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6 December 2019

20-26

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6 December 2019

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400970

21 January 2018

IAP family proteins--suppressors of apoptosis

1 reference

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Structural basis of caspase-7 inhibition by XIAP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400970

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Structural basis for the inhibition of caspase-3 by XIAP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400970

21 January 2018

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400970

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400970

21 January 2018

Structural basis of IAP recognition by Smac/DIABLO

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400970

21 January 2018

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 reference

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21 January 2018

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

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CD95's deadly mission in the immune system

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A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid.

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21 January 2018

Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage

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Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia

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Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400970

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Protein identification based on matrix assisted laser desorption/ionization-post source decay-mass spectrometry

1 reference

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Computational method to predict mitochondrially imported proteins and their targeting sequences

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.

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Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.

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21 January 2018

Expression, purification, and functional analysis of the human serine protease HtrA2

1 reference

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21 January 2018

Mitochondrial control of cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400970

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

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Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

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Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation.

1 reference

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Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

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A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

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Activation of CPP32-like proteases is not sufficient to trigger apoptosis: inhibition of apoptosis by agents that suppress activation of AP24, but not CPP32-like activity

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A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis

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A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection

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The proteolytic procaspase activation network: an in vitro analysis.

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Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs

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7 January 2021

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