Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 (Q28216275)

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P Puigserver

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G Chen

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J Donovan

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Z Wu

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J Rhee

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G Adelmant

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J Stafford

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D K Granner

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C B Newgard

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B M Spiegelman

Regulation of glucose production by the liver

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language of work or name

English

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publication date

13 September 2001

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published in

Nature

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volume

413

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page(s)

131-8

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issue

6852

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cites work

1 reference

7 January 2021

Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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Role of the beta(3)-adrenergic receptor and/or a putative beta(4)-adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator-activated receptor-gamma coactivator-1.

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Rapid in vivo PGC-1 mRNA upregulation in brown adipose tissue of Wistar rats by a beta(3)-adrenergic agonist and lack of effect of leptin

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The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

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Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

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Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression

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Role of CCAAT enhancer-binding protein beta in the thyroid hormone and cAMP induction of phosphoenolpyruvate carboxykinase gene transcription

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The orphan receptor COUP-TF binds to a third glucocorticoid accessory factor element within the phosphoenolpyruvate carboxykinase gene promoter

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A tripartite array of transcription factor binding sites mediates cAMP induction of phosphoenolpyruvate carboxykinase gene transcription and its inhibition by insulin

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Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene

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A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen

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Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1

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The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

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Activation of PPARgamma coactivator-1 through transcription factor docking

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Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal rats

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Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia.

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Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.

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Metabolic Impact of Adenovirus-mediated Overexpression of the Glucose-6-phosphatase Catalytic Subunit in Hepatocytes

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Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

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Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

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Metabolic engineering with recombinant adenoviruses

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Use of recombinant adenovirus for metabolic engineering of mammalian cells.

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The antihyperglycaemic effect of metformin: therapeutic and cellular mechanisms

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Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

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Identifiers

DOI

10.1038/35093050

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

561279

1040559175

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561279

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference