Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man (Q28216498)

Europe PubMed Central

title

Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man (English)

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author name string

Muriel Boube

1

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Laurent Joulia

2

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David L Cribbs

3

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Henri-Marc Bourbon

Conserved structures of mediator and RNA polymerase II holoenzyme

4

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language of work or name

English

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publication date

26 July 2002

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published in

Cell

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volume

110

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issue

2

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page(s)

143-51

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cites work

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Contact with a component of the polymerase II holoenzyme suffices for gene activation

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The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II.

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Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification

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Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein

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Genetics of transcriptional regulation in yeast: connections to the RNA polymerase II CTD.

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Structural organization of yeast and mammalian mediator complexes

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A mediator required for activation of RNA polymerase II transcription in vitro

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Surf5: a gene in the tightly clustered mouse surfeit locus is highly conserved and transcribed divergently from the rpL7A (Surf3) gene

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Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis

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Negative effect of the transcriptional activator GAL4

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Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes

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Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells

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Mediator--a universal complex in transcriptional regulation

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Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation

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Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes

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Association of an activator with an RNA polymerase II holoenzyme

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Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases

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Dissecting the regulatory circuitry of a eukaryotic genome

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Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action

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A comprehensive two-hybrid analysis to explore the yeast protein interactome

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The structural and functional organization of the yeast mediator complex

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A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

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A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

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An RNA polymerase II holoenzyme responsive to activators

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amiB, a novel gene required for the growth/differentiation transition in Dictyostelium

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Eukaryotic transcriptional control

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Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation

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The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans.

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Transcription of eukaryotic protein-coding genes

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Orchestrated response: a symphony of transcription factors for gene control

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Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

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Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells

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The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs

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Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

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Mediator of Transcriptional Regulation

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The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

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Mediator protein mutations that selectively abolish activated transcription

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Transcriptional coactivator complexes

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Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

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The ancient regulatory-protein family of WD-repeat proteins

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Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters

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Mediator complexes and transcription.

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7 January 2021

Functional connections between mediator components and general transcription factors of Saccharomyces cerevisiae

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sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction

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Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe

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Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells

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Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit

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7 January 2021

Structure, function, and activator-induced conformations of the CRSP coactivator

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A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.

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Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice

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7 January 2021

Characterization of mediator complexes from HeLa cell nuclear extract

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7 January 2021

The RNA polymerase II machinery: structure illuminates function

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7 January 2021

A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene

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7 January 2021