Estrogen receptor phosphorylation (Q28217134)

The nuclear receptor superfamily: the second decade

Europe PubMed Central

title

Estrogen receptor phosphorylation (English)

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Deborah A Lannigan

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language of work or name

English

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publication date

January 2003

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published in

Steroids

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volume

68

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issue

1

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page(s)

1-9

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cites work

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Estradiol-induced phosphorylation of serine 118 in the estrogen receptor is independent of p42/p44 mitogen-activated protein kinase

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Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk

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An update on estrogen receptors

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Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta

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Selective expression of estrogen receptor alpha and beta isoforms in human pituitary tumors

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Expression of estrogen receptor alpha mRNA and protein variants in human endometrial carcinoma

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Differential expression and regulation of estrogen receptors (ERs) in rat pituitary and cell lines: estrogen decreases ERalpha protein and estrogen responsiveness

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The structure of the nuclear hormone receptors

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Identification of two transactivation domains in the mouse oestrogen receptor

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A c-fos/Estrogen receptor fusion protein promotes cell cycle progression and proliferation of human cancer cell lines

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The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

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Dendritic cell progenitor is transformed by a conditional v-Rel estrogen receptor fusion protein v-RelER.

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Two transcription activation functions in the amino terminus of the mouse estrogen receptor that are affected by the carboxy terminus

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The human estrogen receptor has two independent nonacidic transcriptional activation functions

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The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

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Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

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Molecular determinants of the estrogen receptor-coactivator interface

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Different positioning of the ligand-binding domain helix 12 and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonists

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Molecular basis of agonism and antagonism in the oestrogen receptor

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Uterine estrogen receptor in vivo: phosphorylation of nuclear specific forms on serine residues

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Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta

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Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.

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7 January 2021

Identification of phosphorylation sites in the mouse oestrogen receptor

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Phosphorylation of tyrosine 537 on the human estrogen receptor is required for binding to an estrogen response element

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pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167

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Potentiation of human estrogen receptor alpha transcriptional activation through phosphorylation of serines 104 and 106 by the cyclin A-CDK2 complex

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Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

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Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

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Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation

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Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7

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Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity

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Estrogen induces a rapid secretion of amyloid beta precursor protein via the mitogen-activated protein kinase pathway

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Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-alpha knock-out mice.

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Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor

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Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain

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Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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7 January 2021

Phosphorylation of human estrogen receptor alpha by protein kinase A regulates dimerization

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7 January 2021

Function of estrogen receptor tyrosine 537 in hormone binding, DNA binding, and transactivation.

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7 January 2021

Properties of a purified estradiol-dependent calf uterus tyrosine kinase

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7 January 2021

Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1

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Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha

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Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes

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Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway.

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7 January 2021

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

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7 January 2021

Estrogen receptor activation function 1 works by binding p160 coactivator proteins

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7 January 2021

Growth factors signal to steroid receptors through mitogen-activated protein kinase regulation of p160 coactivator activity

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7 January 2021

Involvement of cyclic AMP response element binding protein (CREB) and estrogen receptor phosphorylation in the synergistic activation of the estrogen receptor by estradiol and protein kinase activators

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Regulation of the functional interaction between cyclin D1 and the estrogen receptor

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CDK-independent activation of estrogen receptor by cyclin D1

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Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4

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Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein.

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Ligand-independent activation of the oestrogen receptor by mutation of a conserved tyrosine

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Cdc25B functions as a novel coactivator for the steroid receptors

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Serine/threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling

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Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway

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Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF

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Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis

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Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases

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Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium

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Linkage of Rapid Estrogen Action to MAPK Activation by ER -Shc Association and Shc Pathway Activation

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

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Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation

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Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

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Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells

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PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

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Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

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Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta

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Glucocorticoid receptor phosphorylation: overview, function and cell cycle-dependence.

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Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

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Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein

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Proteasome-dependent degradation of the human estrogen receptor

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The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

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Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

4702106

4702106

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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