Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1 (Q28217158)

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6 December 2019

title

Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1 (English)

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6 December 2019

3

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6 December 2019

Melanie H. Cobb

series ordinal

4

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6 December 2019

2

Angelique W Whitehurst

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6 December 2019

author name string

Fred L Robinson

series ordinal

1

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6 December 2019

language of work or name

English

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publication date

31 January 2002

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Journal of Biological Chemistry

6 December 2019

published in

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6 December 2019

volume

277

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6 December 2019

issue

17

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6 December 2019

page(s)

14844-14852

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

6 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Identification of an Activator of the Microtubule‐Associated Protein 2 Kinases ERK1 and ERK2 in PC12 Cells Stimulated with Nerve Growth Factor or Bradykinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Okadaic acid activates microtubule-associated protein kinase in quiescent fibroblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Raf-1 activates MAP kinase-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Molecular determinants that mediate selective activation of p38 MAP kinase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Identification of MAP kinase domains by redirecting stress signals into growth factor responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

The N-terminal ERK-binding site of MEK1 is required for efficient feedback phosphorylation by ERK2 in vitro and ERK activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

A conserved docking motif in MAP kinases common to substrates, activators and regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Protein modification: docking sites for kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Docking domains and substrate-specificity determination for MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Complex formation between RAS and RAF and other protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Crystallization and preliminary X-ray studies of extracellular signal-regulated kinase-2/MAP kinase with an incorporated His-tag

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Mechanism of activation of ERK2 by dual phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Interdependent domains controlling the enzymatic activity of mitogen-activated protein kinase kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Crystal structure of cyclin-dependent kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Extracellular signal-regulated kinases 2 autophosphorylates on a subset of peptides phosphorylated in intact cells in response to insulin and nerve growth factor: analysis by peptide mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Phosphorylation of MAP Kinases by MAP/ERK Involves Multiple Regions of MAP Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Contributions of the Mitogen-activated Protein (MAP) Kinase Backbone and Phosphorylation Loop to MEK Specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Identification of a cytoplasmic-retention sequence in ERK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Isolation of effector-selective Ras mutants by yeast two-hybrid screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

Activity of the MAP kinase ERK2 is controlled by a flexible surface loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107776200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107776200

2 references

Consolidated OpenCitations Corpus – April 2017

1762112

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6 December 2019

1762112

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

1762112