Viruses and interferon: a fight for supremacy (Q28220397)

The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion

31 March 2020

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How does interferon exert its cell growth inhibitory effect?

31 March 2020

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Interferons alpha and beta as immune regulators--a new look

31 March 2020

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Type I interferons: expression and signalization.

31 March 2020

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A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses

31 March 2020

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On the role of IRF in host defense

31 March 2020

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Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes

31 March 2020

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Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3

31 March 2020

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Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback

31 March 2020

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Reconstitution of virus-mediated expression of interferon alpha genes in human fibroblast cells by ectopic interferon regulatory factor-7.

31 March 2020

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Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

31 March 2020

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

31 March 2020

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Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

31 March 2020

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Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action

31 March 2020

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Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

31 March 2020

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Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes

31 March 2020

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Mechanism of interferon action: double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons

31 March 2020

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Role of early cytokines, including alpha and beta interferons (IFN-alpha/beta), in innate and adaptive immune responses to viral infections

31 March 2020

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Noncytolytic control of viral infections by the innate and adaptive immune response

31 March 2020

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The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors

31 March 2020

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The growing family of interferon regulatory factors.

31 March 2020

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Viral inhibition of interferon signal transduction

31 March 2020

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Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures

31 March 2020

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Mechanisms of inhibition of the host interferon alpha/beta-mediated antiviral responses by viruses

31 March 2020

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Virus interference. I. The interferon

31 March 2020

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Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication.

31 March 2020

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Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

31 March 2020

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Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses

31 March 2020

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The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

31 March 2020

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Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK

31 March 2020

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The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity

31 March 2020

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The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity

31 March 2020

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Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

31 March 2020

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Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

31 March 2020

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SOCS proteins: negative regulators of cytokine signaling

31 March 2020

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To interfere and to anti-interfere: the interplay between hepatitis C virus and interferon.

31 March 2020

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How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A.

31 March 2020

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Hepatitis C virus and interferon resistance: it's more than just PKR.

31 March 2020

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Novel cell culture systems for the hepatitis C virus

31 March 2020

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Molecular clones of hepatitis C virus: applications to animal models

31 March 2020

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Hepatitis C virus resistance to antiviral therapy.

31 March 2020

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Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes

31 March 2020

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Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region

31 March 2020

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Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection

31 March 2020

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Why is the interferon sensitivity-determining region (ISDR) system useful in Japan?

31 March 2020

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

31 March 2020

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Efficient initiation of HCV RNA replication in cell culture

31 March 2020

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Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

31 March 2020

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Effect of alpha interferon on the hepatitis C virus replicon

31 March 2020

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HSV.com: maneuvering the internetworks of viral neuropathogenesis and evasion of the host defense

31 March 2020

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Induction of interferon-alpha by glycoprotein D of herpes simplex virus: a possible role of chemokine receptors

31 March 2020

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Molecular cross-talk between the TRAIL and interferon signaling pathways.

31 March 2020

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Activation of interferon response factor-3 in human cells infected with herpes simplex virus type 1 or human cytomegalovirus

31 March 2020

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Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection

31 March 2020

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Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replication

31 March 2020

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The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/beta

31 March 2020

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The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

31 March 2020

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The herpes simplex virus type 1 U(S)11 protein interacts with protein kinase R in infected cells and requires a 30-amino-acid sequence adjacent to a kinase substrate domain

31 March 2020

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Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

31 March 2020

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Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 protein

31 March 2020

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Bioterrorism. Smallpox vaccinations: how much protection remains?

31 March 2020

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Smallpox: anything to declare?

31 March 2020

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Receptors for gamma-interferon encoded by poxviruses: implications for the unknown origin of vaccinia virus.

31 March 2020

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Soluble interferon-gamma receptors encoded by poxviruses

31 March 2020

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31 March 2020

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Use of chemokine receptors by poxviruses

31 March 2020

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Cytokine receptors encoded by poxviruses: a lesson in cytokine biology.

31 March 2020

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Virus-encoded receptors for cytokines and chemokines

31 March 2020

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Vaccinia virus B18R gene encodes a type I interferon-binding protein that blocks interferon alpha transmembrane signaling

31 March 2020

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Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity

31 March 2020

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Vaccinia virus vectors with an inactivated gamma interferon receptor homolog gene (B8R) are attenuated In vivo without a concomitant reduction in immunogenicity

31 March 2020

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Effect of IFN-gamma receptor gene deletion on vaccinia virus virulence

31 March 2020

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Characterization of a vaccinia virus-encoded double-stranded RNA-binding protein that may be involved in inhibition of the double-stranded RNA-dependent protein kinase

31 March 2020

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The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

31 March 2020

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Distinct patterns of IFN sensitivity observed in cells infected with vaccinia K3L- and E3L- mutant viruses

31 March 2020

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Vaccinia virus-encoded elF-2α homolog abrogates the antiviral effect of interferon

31 March 2020

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Analysis of the complete genome of smallpox variola major virus strain Bangladesh-1975.

31 March 2020

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Comparison of the genetic maps of variola and vaccinia viruses

31 March 2020

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The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation

31 March 2020

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Vaccinia virus E3L protein is an inhibitor of the interferon (i.f.n.)-induced 2-5A synthetase enzyme.

31 March 2020

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IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

31 March 2020

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Vaccinia virus E3L interferon resistance protein inhibits the interferon-induced adenosine deaminase A-to-I editing activity

31 March 2020

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Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model

31 March 2020

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Vaccinia virus blocks gamma interferon signal transduction: viral VH1 phosphatase reverses Stat1 activation

31 March 2020

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Using DNA microarrays to study host-microbe interactions

31 March 2020

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Virogenomics: a novel approach to antiviral drug discovery

31 March 2020

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How the host 'sees' pathogens: global gene expression responses to infection.

31 March 2020

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Proteomics in the post-genome age.

31 March 2020

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A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

31 March 2020

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Post-genomic virology: the impact of bioinformatics, microarrays and proteomics on investigating host and pathogen interactions.

31 March 2020

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A new approach to decoding life: systems biology

31 March 2020

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Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

31 March 2020

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Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B.

31 March 2020

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Herpes simplex virus triggers and then disarms a host antiviral response

31 March 2020

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Global impact of influenza virus on cellular pathways is mediated by both replication-dependent and -independent events

31 March 2020

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A comprehensive view of regulation of gene expression by double-stranded RNA-mediated cell signaling

31 March 2020

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Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation

31 March 2020

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Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

31 March 2020

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Effects of mutation in hepatitis C virus nonstructural protein 5A on interferon resistance mediated by inhibition of PKR kinase activity in mammalian cells

31 March 2020

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Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response

31 March 2020

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An altered cellular response to interferon and up-regulation of interleukin-8 induced by the hepatitis C viral protein NS5A uncovered by microarray analysis

31 March 2020

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DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection

31 March 2020

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TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

31 March 2020

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Toll-like receptor 2 and 4 surface expressions on human monocytes are modulated by interferon-gamma and macrophage colony-stimulating factor

31 March 2020

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IFNs activate toll-like receptor gene expression in viral infections

31 March 2020

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Toll-like receptors in the induction of the innate immune response

31 March 2020

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

31 March 2020

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Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

31 March 2020

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TIRAP: an adapter molecule in the Toll signaling pathway

31 March 2020

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Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

31 March 2020

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A road map for those who don't know JAK-STAT

31 March 2020

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The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus

31 March 2020

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The Janus kinase family of protein tyrosine kinases and their role in signaling

31 March 2020

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

31 March 2020

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Global epidemiology of influenza: past and present.

31 March 2020

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Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes

31 March 2020

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Integrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virus

31 March 2020

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Applications of DNA shuffling to pharmaceuticals and vaccines

31 March 2020

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Artificial evolution by DNA shuffling.

31 March 2020

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Evolution of a human immunodeficiency virus type 1 variant with enhanced replication in pig-tailed macaque cells by DNA shuffling

31 March 2020

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Evolution of a cytokine using DNA family shuffling

31 March 2020

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Mx proteins: mediators of innate resistance to RNA viruses.

31 March 2020

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7 January 2021

Vaccinia, cowpox, and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificity

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7 January 2021

The vaccinia virus K3L gene product potentiates translation by inhibiting double-stranded-RNA-activated protein kinase and phosphorylation of the alpha subunit of eukaryotic initiation factor 2

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7 January 2021

The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

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7 January 2021