Sustained expression of Mect1-Maml2 is essential for tumor cell growth in salivary gland cancers carrying the t(11;19) translocation (Q28237714)

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S Modi

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A B Coxon

4

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H Oh

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F J Kaye

Clear cell hidradenoma of the skin-a third tumor type with a t(11;19)--associated TORC1-MAML2 gene fusion

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language of work or name

English

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publication date

5 October 2006

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published in

Oncogene

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volume

25

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issue

45

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page(s)

6128-32

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cites work

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Mect1-Maml2 fusion oncogene linked to the aberrant activation of cyclic AMP/CREB regulated genes

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A mucoepidermoid carcinoma of minor salivary gland with t(11;19)(q21;p13.1) as the only karyotypic abnormality

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Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors

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Molecular analyses of the candidate tumor suppressor gene, PLAGL1, in benign and malignant salivary gland tumors

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Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling

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Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer

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Salivary gland tumours

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A child with a t(11;19)(q14-21;p12) in a pulmonary mucoepidermoid carcinoma

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Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma

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Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

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t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway

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Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation

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Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors

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