N-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecan (Q28238572)

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Mitsuhiro Hoshijima

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Daisuke Araki

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Takashi Nishida

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Satoshi Kubota

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Masaharu Takigawa

CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1

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language of work or name

English

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publication date

27 May 2009

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published in

Biochemical Journal

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volume

420

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issue

3

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page(s)

413-20

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cites work

1 reference

Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan

21 April 2017

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The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor is a receptor for connective tissue growth factor

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Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA

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Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

21 April 2017

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Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily

21 April 2017

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Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions

21 April 2017

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Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan

21 April 2017

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Role of CCN2/CTGF/Hcs24 in bone growth

21 April 2017

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Role of CTGF/HCS24/ecogenin in skeletal growth control

21 January 2018

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Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro

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A novel integrin alpha5beta1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cells

21 January 2018

1 reference

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Structure and function of aggrecan

21 January 2018

1 reference

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Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA.

21 January 2018

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Demonstration of receptors specific for connective tissue growth factor on a human chondrocytic cell line (HCS-2/8).

21 January 2018

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Downregulation of rheumatoid arthritis-related antigen RA-A47 (HSP47/colligin-2) in chondrocytic cell lines induces apoptosis and cell-surface expression of RA-A47 in association with CD9.

21 January 2018

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Downregulation of a rheumatoid arthritis-related antigen (RA-A47) by ra-a47 antisense oligonucleotides induces inflammatory factors in chondrocytes

21 January 2018

1 reference

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Fibulin-1 is a ligand for the C-type lectin domains of aggrecan and versican

21 January 2018

1 reference

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Alternative splicing in the aggrecan G3 domain influences binding interactions with tenascin-C and other extracellular matrix proteins

21 January 2018

1 reference

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The heparin-binding 10 kDa fragment of connective tissue growth factor (CTGF) containing module 4 alone stimulates cell adhesion

21 January 2018

1 reference

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Dwarfism and age-associated spinal degeneration of heterozygote cmd mice defective in aggrecan

21 January 2018

1 reference

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A mutation in the variable repeat region of the aggrecan gene (AGC1) causes a form of spondyloepiphyseal dysplasia associated with severe, premature osteoarthritis

21 January 2018

1 reference

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