Signaling of type II oncostatin M receptor (Q28241135)

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C Guillet

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M Fourcin

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C Olivier

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J Veziers

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A Pouplard-Barthelaix

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H Gascan

Journal of Biological Chemistry

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language of work or name

English

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publication date

20 June 1997

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published in

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volume

272

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issue

25

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page(s)

15760-4

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cites work

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6

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Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells

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Identification of a major growth factor for AIDS-Kaposi's sarcoma cells as oncostatin M

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Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells

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The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

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Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

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Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

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STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

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Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

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Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

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Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein

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gp130 transducing receptor cross-linking is sufficient to induce interleukin-6 type responses

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CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

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Signaling of the cardiotrophin-1 receptor. Evidence for a third receptor component.

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements

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