Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis (Q28242612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21734707%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis (English)

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6 February 2020

1

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6 February 2020

Florian Karreth

2

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6 February 2020

Timothy J Humpton

3

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Christine A Iacobuzio-Donahue

6 February 2020

14

object named as

Christine Iacobuzio-Donahue

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Ralph H Hruban

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6 February 2020

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David A Tuveson

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Charles J Yeo

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6 February 2020

8

Kenneth H Yu

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6 February 2020

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Eric S Calhoun

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6 February 2020

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Jordan M Winter

1 reference

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6 February 2020

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Francesca Scrimieri

1 reference

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6 February 2020

4

Aarthi Gopinathan

1 reference

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6 February 2020

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Kristopher Frese

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6 February 2020

author name string

Cong Wei

5

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6 February 2020

Dipti Mangal

7

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6 February 2020

Scott E Kern

15

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6 February 2020

Ian A Blair

16

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6 February 2020

language of work or name

English

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publication date

6 July 2011

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6 February 2020

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6 February 2020

volume

475

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6 February 2020

page(s)

106-109

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6 February 2020

issue

7354

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Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes

6 February 2020

cites work

1 reference

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The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

20 March 2017

1 reference

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

6 April 2017

1 reference

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Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2·Keap1·Cul3 complex and recruiting Nrf2·Maf to the antioxidant response element enhancer

20 March 2017

1 reference

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Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

20 March 2017

1 reference

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The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

20 March 2017

1 reference

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

20 March 2017

1 reference

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Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

20 March 2017

1 reference

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Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells

20 March 2017

1 reference

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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

29 September 2017

1 reference

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Distinct thresholds govern Myc's biological output in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

Determination of cellular redox status by stable isotope dilution liquid chromatography/mass spectrometry analysis of glutathione and glutathione disulfide

29 September 2017

1 reference

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Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

Reactive species-mediated regulation of cell signaling and the cell cycle: the role of MAPK.

29 September 2017

1 reference

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Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

29 September 2017

1 reference

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

29 September 2017

1 reference

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Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

Altered detoxification status and increased resistance to oxidative stress by K-ras transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404470

The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation.

2 June 2018

1 reference

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Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

27 November 2018

1 reference

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Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines.

27 November 2018

1 reference

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Allelotype of pancreatic adenocarcinoma using xenograft enrichment

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21734707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21734707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10189

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21734707%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 February 2020

1011803417

0 references

1 reference

2 references

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6 February 2020

2 references

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