Cloning and expression of an alternatively spliced mRNA encoding a soluble form of the human interleukin-6 signal transducer gp130 (Q28246143)

2

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N Mechti

3

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X G Zhang

4

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M Svenson

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K Bendtzen

6

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B Klein

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

7

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language of work or name

English

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publication date

28 July 1997

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published in

FEBS Letters

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volume

412

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issue

2

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page(s)

379-84

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cites work

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CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

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The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

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Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130

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Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

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The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development

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Molecular cloning and characterization of the human interleukin-11 receptor alpha-chain gene, IL11RA, located on chromosome 9p13

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Molecular cloning and expression of an IL-6 signal transducer, gp130

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Soluble receptors for cytokines and growth factors: generation and biological function

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Mediation of interleukin-11-dependent biological responses by a soluble form of the interleukin-11 receptor

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The soluble interleukin-6 receptor is generated by shedding

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Differential interleukin-6 (IL-6) responses of three established myeloma cell lines in the presence of soluble human IL-6 receptors

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Organization and expression of eucaryotic split genes coding for proteins

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The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms

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Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit

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Three different cDNAs encoding mouse D-factor/LIF receptor

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Abnormal splicing of the leptin receptor in diabetic mice

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Molecular cloning of rat leptin receptor isoform complementary DNAs--identification of a missense mutation in Zucker fatty (fa/fa) rats

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Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130

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Oncostatin M, leukemia inhibitory factor, and interleukin 6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130.

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Interleukin-6 antisense oligonucleotides inhibit the growth of human myeloma cell lines

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Intracellular interleukin 6 mediates platelet-derived growth factor-induced proliferation of nontransformed cells.

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inferred from DOI database lookup

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based on heuristic

Enhancement of interleukin 6 cytostatic effect on human breast carcinoma cells by soluble IL-6 receptor from urine and reversion by monoclonal antibody

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Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses

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Differential shedding of the two subunits of the interleukin-6 receptor

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Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M

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Increased and highly stable levels of functional soluble interleukin-6 receptor in sera of patients with monoclonal gammopathy

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