Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophy (Q28248750)

2

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Yevgeniya E Koshman

3

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Taehoon Kim

4

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Brenda Russell

5

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Jody L Martin

6

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Alain L Heroux

7

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Seth L Robia

8

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Allen M Samarel

Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy

9

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language of work or name

English

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publication date

1 December 2011

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published in

Cardiovascular Research

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volume

92

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issue

3

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page(s)

409-19

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cites work

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Restoration of resting sarcomere length after uniaxial static strain is regulated by protein kinase Cepsilon and focal adhesion kinase

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Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy

20 March 2017

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A role for focal adhesion kinase in phenylephrine-induced hypertrophy of rat ventricular cardiomyocytes

20 March 2017

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Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts

20 March 2017

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Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response

20 March 2017

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Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice

20 March 2017

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Nuclear compartmentalization of FAK and FRNK in cardiac myocytes

20 March 2017

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Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype

20 March 2017

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Focal adhesion kinase: in command and control of cell motility

20 March 2017

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Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth

7 April 2017

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Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions

29 September 2017

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Regulatory autophosphorylation sites on protein kinase C-delta at threonine-141 and threonine-295.

29 September 2017

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Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice

29 September 2017

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Targeting of FAK Ser910 by ERK5 and PP1delta in non-stimulated and phorbol ester-stimulated cells

29 September 2017

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Coincident regulation of PKCdelta in human platelets by phosphorylation of Tyr311 and Tyr565 and phospholipase C signalling

29 September 2017

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Protein kinase Cepsilon (PKCepsilon) and Src control PKCdelta activation loop phosphorylation in cardiomyocytes

29 September 2017

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Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy

29 September 2017

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Costameres, focal adhesions, and cardiomyocyte mechanotransduction.

29 September 2017

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FAK phosphorylation sites mapped by mass spectrometry

29 September 2017

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Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells

29 September 2017

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Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.

29 September 2017

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MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src

29 September 2017

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c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.

29 September 2017

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Serine phosphorylation of focal adhesion kinase in interphase and mitosis: a possible role in modulating binding to p130(Cas).

29 September 2017

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The role of the cytoskeleton in heart failure

29 September 2017

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Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I.

29 September 2017

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PDGF and FGF induce focal adhesion kinase (FAK) phosphorylation at Ser-910: dissociation from Tyr-397 phosphorylation and requirement for ERK activation

2 June 2018

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Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes

2 June 2018

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Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation

2 June 2018

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Load-induced focal adhesion kinase activation in the myocardium: role of stretch and contractile activity

2 June 2018

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The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation.

21 January 2018

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Subcellular redistribution of focal adhesion kinase and its related nonkinase in hypertrophic myocardium

21 January 2018

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Protein kinase C delta induces Src kinase activity via activation of the protein tyrosine phosphatase PTP alpha

21 January 2018

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Regulation of Ras·GTP Loading and Ras-Raf Association in Neonatal Rat Ventricular Myocytes by G Protein-coupled Receptor Agonists and Phorbol Ester

21 January 2018

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Striated muscle-specific beta(1D)-integrin and FAK are involved in cardiac myocyte hypertrophic response pathway.

21 January 2018

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c-Src activation plays a role in endothelin-dependent hypertrophy of the cardiac myocyte

27 November 2018

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Distribution of vinculin in the Z-disk of striated muscle: analysis by laser scanning confocal microscopy

27 November 2018

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12 December 2020

Endothelin ETA receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload

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12 December 2020

Loss of protein kinase C function induces an apoptotic response

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12 December 2020

Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes

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12 December 2020

Endothelin signalling in the cardiac myocyte and its pathophysiological relevance

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12 December 2020

Endothelin-induced cardiac myocyte hypertrophy: role for focal adhesion kinase

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12 December 2020