Microbial cell individuality and the underlying sources of heterogeneity (Q28252446)

Nature Reviews Microbiology

Europe PubMed Central

title

Microbial cell individuality and the underlying sources of heterogeneity (English)

0 references

1 reference

Simon V Avery

1

0 references

language of work or name

English

0 references

publication date

August 2006

0 references

published in

0 references

volume

4

0 references

page(s)

577-87

0 references

issue

8

0 references

cites work

Stochastic gene expression in a single cell

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Cell cycle‐ and age‐dependent activation of Sod1p drives the formation of stress resistant cell subpopulations within clonal yeast cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Single-cell microbiology: tools, technologies, and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Regulated cell-to-cell variation in a cell-fate decision system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Stress and the single cell: intrapopulation diversity is a mechanism to ensure survival upon exposure to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phenotypic heterogeneity: differential stress resistance among individual cells of the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Stochastic gene expression in fluctuating environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phenotypic diversity, population growth, and information in fluctuating environments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

A yeast prion provides a mechanism for genetic variation and phenotypic diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Control of stochasticity in eukaryotic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Stochasticity in gene expression: from theories to phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Noise in gene expression: origins, consequences, and control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Filtering transcriptional noise during development: concepts and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Copper/zinc-Superoxide dismutase is required for oxytetracycline resistance of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Tandem genetic duplications in phage and bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Playing Dr Jekyll and Mr Hyde: combined mechanisms of phase variation in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phase and antigenic variation in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Regulation of antigen gene expression in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Antigenic variation in Babesia bovis occurs through segmental gene conversion of the ves multigene family, within a bidirectional locus of active transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Molecular switches--the ON and OFF of bacterial phase variation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

The Mechanism by which DNA Adenine Methylase and PapI Activate the Pap Epigenetic Switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

The central roles of telomeres and subtelomeres in antigenic variation in African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

The epigenetic control of antigenic variation in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Flocculation, adhesion and biofilm formation in yeasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

High-frequency switching of colony morphology in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

"White-opaque transition": a second high-frequency switching system in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phenotypic switching and mating type switching of Candida glabrata at sites of colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phenotypic switching in Candida glabrata accompanied by changes in expression of genes with deduced functions in copper detoxification and stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Mating-type locus homozygosis, phenotypic switching and mating: a unique sequence of dependencies in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Switch of phenotype as an escape mechanism of the intruder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Evolution of a combinatorial transcriptional circuit: a case study in yeasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Chromosome loss followed by duplication is the major mechanism of spontaneous mating-type locus homozygosis in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

The histone deacetylase genes HDA1 and RPD3 play distinct roles in regulation of high-frequency phenotypic switching in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phenotypic switching in Candida albicans is controlled by a SIR2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Mutants of Escherichia coli K-12 exhibiting reduced killing by both quinolone and beta-lactam antimicrobial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Persister cells, the biofilm matrix and tolerance to metal cations in biofilm and planktonic Pseudomonas aeruginosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phenotypic tolerance: antibiotic enrichment of noninherited resistance in bacterial populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Biofilms and planktonic cells of Pseudomonas aeruginosa have similar resistance to killing by antimicrobials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Persister cells and the riddle of biofilm survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Bacterial persistence as a phenotypic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Hetero-resistance: an under-recognised confounder in diagnosis and therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Programmed death in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Persister cells and tolerance to antimicrobials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Clonal variation in maximum specific growth rate and susceptibility towards antimicrobials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Bacterial persistence: a model of survival in changing environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Heterogeneity of stress gene expression and stress resistance among individual cells of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Translation termination efficiency can be regulated in Saccharomyces cerevisiae by environmental stress through a prion-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Diversify or die: generation of diversity in response to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Hsp90 as a capacitor for morphological evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Evolutionary capacitance as a general feature of complex gene networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Effect of cell cycle position on thermotolerance in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Oscillatory nucleocytoplasmic shuttling of the general stress response transcriptional activators Msn2 and Msn4 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Measurement of SOS expression in individual Escherichia coli K-12 cells using fluorescence microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

A genomewide oscillation in transcription gates DNA replication and cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Cellular stress responses oscillate in synchronization with the ultradian oscillation of energy metabolism in the yeast Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Analysis of the upstream regulatory region of the GTS1 gene required for its oscillatory expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Silent repair accounts for cell cycle specificity in the signaling of oxidative DNA lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Differential oxidative damage and expression of stress defence regulons in culturable and non-culturable Escherichia coli cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Asymmetric inheritance of oxidatively damaged proteins during cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Flow cytometric investigation of heterogeneous copper-sensitivity in asynchronously grown Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Induction of phenotypes resembling CuZn-superoxide dismutase deletion in wild-type yeast cells: an in vivo assay for the role of superoxide in the toxicity of redox-cycling compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Oxidative protein damage causes chromium toxicity in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Making sense of it all: bacterial chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Optimizing the success of random searches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

From molecular noise to behavioural variability in a single bacterium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Non-genetic individuality: chance in the single cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Origins of individual swimming behavior in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Noise in gene expression as the source of non-genetic individuality in the chemotactic response of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Binding of the chemotaxis response regulator CheY to the isolated, intact switch complex of the bacterial flagellar motor: lack of cooperativity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Co-regulation of acetylation and phosphorylation of CheY, a response regulator in chemotaxis of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Design principles of a bacterial signalling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Cell population heterogeneity during growth of Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Gene expression from plasmids containing the araBAD promoter at subsaturating inducer concentrations represents mixed populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Non-genetic population heterogeneity studied by in situ polymerase chain reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Prediction and measurement of an autoregulatory genetic module

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phenotypic variation in bacteria: the role of feedback regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Noise in eukaryotic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Revisited gene regulation in bacteriophage lambda.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

The essential role of the cro gene in lytic development by bacteriophage lambda

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

hflB, a new Escherichia coli locus regulating lysogeny and the level of bacteriophage lambda cII protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Bistability in the Bacillus subtilis K-state (competence) system requires a positive feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Cell individuality: the bistability of competence development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Phosphatases modulate the bistable sporulation gene expression pattern in Bacillus subtilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Cannibalism by sporulating bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Stochastic processes influence stationary-phase decisions in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Evidence that entry into sporulation in Bacillus subtilis is governed by a gradual increase in the level and activity of the master regulator Spo0A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

An excitable gene regulatory circuit induces transient cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Gene regulation at the single-cell level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Coherence and timing of cell cycle start examined at single-cell resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Probing gene expression in live cells, one protein molecule at a time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Regulation of noise in the expression of a single gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Real-time kinetics of gene activity in individual bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Origins of extrinsic variability in eukaryotic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Stochastic protein expression in individual cells at the single molecule level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

The intricate workings of a bacterial epigenetic switch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Evolutionary conservation of prion-forming abilities of the yeast Sup35 protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Differential response to UV stress and DNA damage during the yeast replicative life span

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Involvement of glutathione in the regulation of respiratory oscillation during a continuous culture of Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Investigating phenotypes resulting from a lack of superoxide dismutase in bacterial null mutants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

Single-cell Analysis of λ Immunity Regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460

inferred from DOI database lookup

7 January 2021

based on heuristic

Rapid, transient fluconazole resistance in Candida albicans is associated with increased mRNA levels of CDR.

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1460