Biosynthesis and function of gliotoxin in Aspergillus fumigatus (Q28253295)

aminotransferase gliI, putative

6 February 2019

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6 February 2019

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6 February 2019

nonribosomal peptide synthetase gliP

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cytochrome P450 monooxygenase gliC

6 February 2019

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6 February 2019

O-methyltransferase gliM

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glutathione S-transferase gliG

6 February 2019

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gamma-glutamyl cyclotransferase gliK

6 February 2019

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MFS gliotoxin efflux transporter gliA

6 February 2019

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6 February 2019

N-methyltransferase gliN

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cytochrome P450 monooxygenase gliF

6 February 2019

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thioredoxin reductase gliT

6 February 2019

1 reference

Ortholog of Aspergillus brasiliensis : Aspbr1_0199026, Neosartorya fischeri NRRL 181 : NFIA_055440, NFIA_112700, Aspergillus fumigatus A1163 : AFUB_075800 and Aspergillus clavatus NRRL 1 : ACLA_006680

6 February 2019

1 reference

(6S)-6-benzyl-6-hydroxy-1-methoxy-3-methylidenepiperazine-2,5-dione

6 February 2019

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Daniel H Scharf

1

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Thorsten Heinekamp

Thorsten Heinekamp

2

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Christian Hertweck

Christian Hertweck

6

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Axel A Brakhage

5

Axel A Brakhage

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Nicole Remme

3

Nicole Remme

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Peter Hortschansky

4

Applied Microbiology and Biotechnology

Peter Hortschansky

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language of work or name

English

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publication date

January 2012

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18 November 2011

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16 September 2022

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volume

93

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issue

2

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page(s)

467-72

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exact match

https://scigraph.springernature.com/pub.10.1007/s00253-011-3689-1

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cites work

Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites.

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Identification of cryptic products of the gliotoxin gene cluster using NMR-based comparative metabolomics and a model for gliotoxin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

The epipolythiodioxopiperazine (ETP) class of fungal toxins: distribution, mode of action, functions and biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Gliotoxin production by clinical and environmental Aspergillus fumigatus strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Detection of gliotoxin in experimental and human aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Frequency and species distribution of gliotoxin-producing Aspergillus isolates recovered from patients at a tertiary-care cancer center

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Streptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Sub-telomere directed gene expression during initiation of invasive aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Effects of Aspergillus fumigatus gliotoxin and methylprednisolone on human neutrophils: implications for the pathogenesis of invasive aspergillosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Origin and distribution of epipolythiodioxopiperazine (ETP) gene clusters in filamentous ascomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Transannular disulfide formation in gliotoxin biosynthesis and its role in self-resistance of the human pathogen Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Genes differentially expressed in conidia and hyphae of Aspergillus fumigatus upon exposure to human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

An FAD-dependent pyridine nucleotide-disulfide oxidoreductase is involved in disulfide bond formation in FK228 anticancer depsipeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1

Gliotoxin and related epipolythiodioxopiperazines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3689-1