Type I interferons in infectious disease (Q28255842)

Europe PubMed Central

title

Type I interferons in infectious disease (English)

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Anne O'Garra

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Andreas Wack

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object named as

Andreas Wack

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Alan Sher

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object named as

Alan Sher

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author name string

Finlay McNab

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Katrin Mayer-Barber

Nature Reviews Immunology

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language of work or name

English

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publication date

February 2015

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published in

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volume

15

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page(s)

87-103

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issue

2

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cites work

Interferons, interferon-like cytokines, and their receptors

1 reference

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

21 April 2017

1 reference

IL-28A, IL-28B, and IL-29: promising cytokines with type I interferon-like properties

21 April 2017

1 reference

Intrinsic antiviral immunity

21 April 2017

1 reference

Cytosolic sensing of viruses

21 April 2017

1 reference

Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors

21 April 2017

1 reference

Regulation of type I interferon responses

21 April 2017

1 reference

Functional role of type I and type II interferons in antiviral defense

21 April 2017

1 reference

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

21 April 2017

1 reference

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

21 April 2017

1 reference

IFITM3 restricts the morbidity and mortality associated with influenza

21 April 2017

1 reference

The role of host genetics in susceptibility to influenza: a systematic review

21 April 2017

1 reference

Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection

21 April 2017

1 reference

Early B-Cell Activation after West Nile Virus Infection Requires Alpha/Beta Interferon but Not Antigen Receptor Signaling

21 April 2017

1 reference

Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia

21 April 2017

1 reference

Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication

21 April 2017

1 reference

Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway

21 April 2017

1 reference

Exogenous gamma and alpha/beta interferon rescues human macrophages from cell death induced by Bacillus anthracis

21 April 2017

1 reference

Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency

21 April 2017

1 reference

Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-β and AIM2 inflammasome-dependent IL-1β production via its ESX-1 secretion system

21 April 2017

1 reference

Opposing roles for interferon regulatory factor-3 (IRF-3) and type I interferon signaling during plague

21 April 2017

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Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

21 April 2017

1 reference

Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections

21 April 2017

1 reference

Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness

21 April 2017

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Poly I:C enhances susceptibility to secondary pulmonary infections by gram-positive bacteria

21 April 2017

1 reference

Constitutive type I interferon modulates homeostatic balance through tonic signaling

21 April 2017

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IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

21 April 2017

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Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

21 April 2017

1 reference

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

21 April 2017

1 reference

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

21 April 2017

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Regulation of interferon-gamma during innate and adaptive immune responses

21 April 2017

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IFN-λ4: the paradoxical new member of the interferon lambda family

31 March 2020

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Interferon induction and function at the mucosal surface

31 March 2020

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31 March 2020

Immune sensing of DNA

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Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen

31 March 2020

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NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis

31 March 2020

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NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway

31 March 2020

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NOD1 and NOD2 Signaling in Infection and Inflammation.

31 March 2020

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TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway

31 March 2020

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The IRF family transcription factors in immunity and oncogenesis

31 March 2020

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Viral tricks to grid-lock the type I interferon system

31 March 2020

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Tripartite-motif proteins and innate immune regulation

31 March 2020

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Host restriction factor screening: let the virus do the work

31 March 2020

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Virus-specific interferon action. Protection of newborn Mx carriers against lethal infection with influenza virus

31 March 2020

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Type I IFN modulates innate and specific antiviral immunity.

31 March 2020

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Protective role of beta interferon in host defense against influenza A virus

31 March 2020

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The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice

31 March 2020

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Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections

31 March 2020

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Interferon-lambda contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses

31 March 2020

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Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia

31 March 2020

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Inborn errors of human JAKs and STATs

31 March 2020

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Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense

31 March 2020

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Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

31 March 2020

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Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals

31 March 2020

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Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation

31 March 2020

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Interferon induces a unique protein in mouse cells bearing a gene for resistance to influenza virus

31 March 2020

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Interferon-alpha disables dendritic cell precursors: dendritic cells derived from interferon-alpha-treated monocytes are defective in maturation and T-cell stimulation

31 March 2020

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Potent immune response against HIV-1 and protection from virus challenge in hu-PBL-SCID mice immunized with inactivated virus-pulsed dendritic cells generated in the presence of IFN-alpha

31 March 2020

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Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice.

31 March 2020

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Monocyte-derived dendritic cells generated after a short-term culture with IFN-alpha and granulocyte-macrophage colony-stimulating factor stimulate a potent Epstein-Barr virus-specific CD8+ T cell response.

31 March 2020

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Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling

31 March 2020

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Differential regulation of human blood dendritic cell subsets by IFNs

31 March 2020

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Type I interferons produced by dendritic cells promote their phenotypic and functional activation

31 March 2020

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Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon

31 March 2020

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Direct Stimulation of T Cells by Type I IFN Enhances the CD8+ T Cell Response during Cross-Priming

31 March 2020

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IFN-α enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing.

31 March 2020

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Expression of CCR-7, MIP-3beta , and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities

31 March 2020

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Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-α

31 March 2020

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A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

31 March 2020

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Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection

31 March 2020

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Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo

31 March 2020

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Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids

31 March 2020

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Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN.

31 March 2020

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Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells

31 March 2020

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Mice deficient in STAT1 but not STAT2 or IRF9 develop a lethal CD4+ T-cell-mediated disease following infection with lymphocytic choriomeningitis virus.

31 March 2020

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Beta interferon controls West Nile virus infection and pathogenesis in mice

31 March 2020

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CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

31 March 2020

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Antiproliferative action of interferon-α requires components of T-cell-receptor signalling

31 March 2020

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Interferon alpha augments activation-induced T cell death by upregulation of Fas (CD95/APO-1) and Fas ligand expression

31 March 2020

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Virus-induced transient immune suppression and the inhibition of T cell proliferation by type I interferon

31 March 2020

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Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

31 March 2020

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STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma

31 March 2020

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Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-alpha beta responses in T lymphocytes

31 March 2020

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Type I interferons keep activated T cells alive

31 March 2020

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CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion

31 March 2020

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

31 March 2020

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Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation

31 March 2020

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Signal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses.

31 March 2020

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Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by alpha/beta interferon in T lymphocytes.

31 March 2020

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Modulation of STAT1 protein levels: a mechanism shaping CD8 T-cell responses in vivo

31 March 2020

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Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory

31 March 2020

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IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions

31 March 2020

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Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection

31 March 2020

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Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection

31 March 2020

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Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox

31 March 2020

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Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation.

31 March 2020

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A temporal role of type I interferon signaling in CD8+ T cell maturation during acute West Nile virus infection

31 March 2020

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Reciprocal responsiveness to interleukin-12 and interferon-alpha specifies human CD8+ effector versus central memory T-cell fates

31 March 2020

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Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge

31 March 2020

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Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes.

31 March 2020

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Inflammatory monocytes activate memory CD8(+) T and innate NK lymphocytes independent of cognate antigen during microbial pathogen invasion

31 March 2020

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Type I interferons protect T cells against NK cell attack mediated by the activating receptor NCR1.

31 March 2020

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Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.

31 March 2020

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Activation mechanisms of natural killer cells during influenza virus infection

31 March 2020

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Direct action of type I IFN on NK cells is required for their activation in response to vaccinia viral infection in vivo

31 March 2020

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Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection

31 March 2020

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Dendritic cells prime natural killer cells by trans-presenting interleukin 15

31 March 2020

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Cutting edge: IL-15-independent NK cell response to mouse cytomegalovirus infection

31 March 2020

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Differential Responses of Immune Cells to Type I Interferon Contribute to Host Resistance to Viral Infection

31 March 2020

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High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells.

31 March 2020

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Type 1 interferon induction of natural killer cell gamma interferon production for defense during lymphocytic choriomeningitis virus infection

31 March 2020

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Resident bone marrow macrophages produce type 1 interferons that can selectively inhibit interleukin-7-driven growth of B lineage cells

31 March 2020

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Impairment of T and B cell development by treatment with a type I interferon

31 March 2020

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Low-Dose Orally Administered Type I Interferon Reduces Splenic B Cell Numbers in Mice

31 March 2020

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Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

31 March 2020

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Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response

31 March 2020

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Type I IFN receptor signals directly stimulate local B cells early following influenza virus infection

31 March 2020

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Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals.

31 March 2020

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B7-1/2 (CD80/CD86) direct signaling to B cells enhances IgG secretion.

31 March 2020

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TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses

31 March 2020

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Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses

31 March 2020

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Vesicular stomatitis virus glycoprotein displaying retrovirus-like particles induce a type I IFN receptor-dependent switch to neutralizing IgG antibodies

31 March 2020

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B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity

31 March 2020

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Interferons alpha and beta as immune regulators--a new look

31 March 2020

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Pathogenic potential of interferon αβ in acute influenza infection

31 March 2020

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Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections

31 March 2020

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Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

31 March 2020

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Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses

31 March 2020

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Alpha and lambda interferon together mediate suppression of CD4 T cells induced by respiratory syncytial virus

31 March 2020

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Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function

31 March 2020

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Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients.

31 March 2020

1 reference

HIV turns plasmacytoid dendritic cells (pDC) into TRAIL-expressing killer pDC and down-regulates HIV coreceptors by Toll-like receptor 7-induced IFN-alpha

31 March 2020

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CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis

31 March 2020

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Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.

31 March 2020

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Interferon-alpha enhances TRAIL-mediated apoptosis by up-regulating caspase-8 transcription in human hepatoma cells.

31 March 2020

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Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation

31 March 2020

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Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma

31 March 2020

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Persistent LCMV infection is controlled by blockade of type I interferon signaling

31 March 2020

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Blockade of chronic type I interferon signaling to control persistent LCMV infection

31 March 2020

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Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand

31 March 2020

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Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells.

31 March 2020

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Type-I interferon is critical for FasL expression on lung cells to determine the severity of influenza

31 March 2020

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Local blockade of epithelial PDL-1 in the airways enhances T cell function and viral clearance during influenza virus infection

31 March 2020

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The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL.

31 March 2020

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Interferon-inducible effector mechanisms in cell-autonomous immunity

31 March 2020

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Inhibition of chlamydia trachomatis growth by human interferon-alpha: mechanisms and synergistic effect with interferon-gamma and tumor necrosis factor-alpha

31 March 2020

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IFN-alpha beta-dependent, IFN-gamma secretion by bone marrow-derived macrophages controls an intracellular bacterial infection

31 March 2020

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STAT1 regulates IFN-alpha beta- and IFN-gamma-dependent control of infection with Chlamydia pneumoniae by nonhemopoietic cells.

31 March 2020

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Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages

31 March 2020

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Interferons direct an effective innate response to Legionella pneumophila infection

31 March 2020

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Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria

31 March 2020

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Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract

31 March 2020

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Role of interferon in streptococcal infection in the mouse

31 March 2020

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Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10.

31 March 2020

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Type I IFN modulates host defense and late hyperinflammation in septic peritonitis.

31 March 2020

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Cutting edge: a murine, IL-12-independent pathway of IFN-gamma induction by gram-negative bacteria based on STAT4 activation by Type I IFN and IL-18 signaling

31 March 2020

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Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes

31 March 2020

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Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection.

31 March 2020

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Type I interferon production enhances susceptibility to Listeria monocytogenes infection

31 March 2020

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Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes.

31 March 2020

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Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes

31 March 2020

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31 March 2020

12 December 2020

IFN-beta increases listeriolysin O-induced membrane permeabilization and death of macrophages.

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Stimulation of inducible nitric oxide synthase expression by beta interferon increases necrotic death of macrophages upon Listeria monocytogenes infection.

31 March 2020

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A fluorescence reporter model defines "Tip-DCs" as the cellular source of interferon β in murine listeriosis

31 March 2020

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Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes

31 March 2020

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Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma

31 March 2020

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Type I IFNs downregulate myeloid cell IFN-γ receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription.

31 March 2020

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Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway.

31 March 2020

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The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation

31 March 2020

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The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis

31 March 2020

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Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha /beta

31 March 2020

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Expression of the nitric oxide synthase 2 gene is not essential for early control of Mycobacterium tuberculosis in the murine lung

31 March 2020

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Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response

31 March 2020

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Human gene expression profiles of susceptibility and resistance in tuberculosis.

31 March 2020

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Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis

31 March 2020

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Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

31 March 2020

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Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection

31 March 2020

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TPL-2-ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I IFN production

31 March 2020

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Influenza A virus impairs control of Mycobacterium tuberculosis coinfection through a type I interferon receptor-dependent pathway

31 March 2020

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Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo

31 March 2020

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Inhibition of the type I immune responses of human monocytes by IFN-α and IFN-β.

31 March 2020

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Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages

31 March 2020

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Type I IFN induces IL-10 production in an IL-27-independent manner and blocks responsiveness to IFN-γ for production of IL-12 and bacterial killing in Mycobacterium tuberculosis-infected macrophages

31 March 2020

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Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

31 March 2020

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Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

31 March 2020

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Prostaglandin E2 suppresses lipopolysaccharide-stimulated IFN-beta production

31 March 2020

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Targeted prostaglandin E2 inhibition enhances antiviral immunity through induction of type I interferon and apoptosis in macrophages.

31 March 2020

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Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses

31 March 2020

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Dynamic roles of type I and type II IFNs in early infection with Mycobacterium tuberculosis

31 March 2020

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Mycobacterium tuberculosis diverts alpha interferon-induced monocyte differentiation from dendritic cells into immunoprivileged macrophage-like host cells

31 March 2020

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Type I interferon signaling is required for activation of the inflammasome during Francisella infection

31 March 2020

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Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections

31 March 2020

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Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei

31 March 2020

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MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infection

31 March 2020

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TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria

31 March 2020

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Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

31 March 2020

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Type 1 interferon (IFNalpha/beta) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite

31 March 2020

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Regulation of type 2 nitric oxide synthase by type 1 interferons in macrophages infected with Leishmania major

31 March 2020

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Protection against progressive leishmaniasis by IFN-beta.

31 March 2020

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IFN-beta impairs superoxide-dependent parasite killing in human macrophages: evidence for a deleterious role of SOD1 in cutaneous leishmaniasis

31 March 2020

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Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites

31 March 2020

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Type I interferons suppress CD4⁺ T-cell-dependent parasite control during blood-stage Plasmodium infection.

31 March 2020

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Inhibition of Plasmodium yoelii blood-stage malaria by interferon alpha through the inhibition of the production of its target cell, the reticulocyte

31 March 2020

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Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice

31 March 2020

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Classical CD11c+ dendritic cells, not plasmacytoid dendritic cells, induce T cell responses to Plasmodium chabaudi malaria.

31 March 2020

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Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

31 March 2020

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Type I IFNs stimulate nitric oxide production and resistance to Trypanosoma cruzi infection

31 March 2020

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TLR-dependent induction of IFN-beta mediates host defense against Trypanosoma cruzi

31 March 2020

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Type I IFNs play a role in early resistance, but subsequent susceptibility, to the African trypanosomes

31 March 2020

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Type I interferons increase host susceptibility to Trypanosoma cruzi infection

31 March 2020

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Role of IFN-alpha/beta and IL-12 in the activation of natural killer cells and interferon-gamma production during experimental infection with Trypanosoma cruzi

31 March 2020

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IFN-alpha/beta signaling is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis

31 March 2020

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Recognition of yeast nucleic acids triggers a host-protective type I interferon response

31 March 2020

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Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.

31 March 2020

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Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling

31 March 2020

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Conidia but not yeast cells of the fungal pathogen Histoplasma capsulatum trigger a type I interferon innate immune response in murine macrophages.

31 March 2020

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Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

31 March 2020

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STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis

31 March 2020

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Type I interferon induction during influenza virus infection increases susceptibility to secondary Streptococcus pneumoniae infection by negative regulation of γδ T cells

31 March 2020

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Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

31 March 2020

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Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

31 March 2020

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Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses

31 March 2020

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Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections

31 March 2020

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Role of the microbiota in immunity and inflammation

31 March 2020

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Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota.

31 March 2020

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Commensal bacteria calibrate the activation threshold of innate antiviral immunity

31 March 2020

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Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration.

31 March 2020

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Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-β.

31 March 2020

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Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A

31 March 2020

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12 December 2020

Effects of IL-12 on the response and susceptibility to experimental viral infections

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12 December 2020

Natural and recombinant interferons inhibit epithelial cell invasion by Shigella spp.

1 reference

12 December 2020

Interferon-induced inhibition of Chlamydia trachomatis: dissociation from antiviral and antiproliferative effects

1 reference

12 December 2020

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

1 reference

12 December 2020

The role of interferon in influenza virus tissue tropism

1 reference

12 December 2020

Mouse fibroblast interferon modifies Salmonella typhimurium infection in infant mice.

1 reference

12 December 2020

The regulation of inflammation by interferons and their STATs

1 reference

12 December 2020

Effect of Interferon and Interferon Inducers on Infections with a Nonviral Intracellular Microorganism, Chlamydia trachomatis

1 reference

12 December 2020